LC/MS Fundamentals & Applications (8-10 November, 2010)
Singapore
Price: US$ 1600 (for 3 days, including coffee/tea, lunch and all workshop materials)
10% EARLY BIRD DISCOUNT APPLIED TO ALL REGISTRATIONS MADE ON OR BEFORE 17 SEPTEMBER
Who Should Attend?
Researchers, practitioners, technicians, and others who are currently using LC, LC/MS, or plan to use LC/MS in the future, and those dealing with data produced by LC/MS. This course is designed to provide a practical overview. Chromatographers just embarking on the technique will gain insight on how to select the appropriate instrument for different applications, and those currently using LC/MS and its data will develop an appreciation for, and an understanding of, the complexities of the data generated.
How You’ll Benefit from This Course:
1. Understand the operational fundamentals of liquid chromatography, mass spectrometry, and the commercially available LC/MS interfaces.
2. Receive an overview of LC/MS applications in pharmaceutical, chemical, and biotechnology industries plus information on forensic and toxicological applications
3. Learn how to modify existing HPLC methods to optimize results when moving to LC/MS.
4. Find out how to use LC/MS to obtain qualitative information about your samples; from simple molecular weight determinations to structural analysis through spectral interpretation.
Course Topics:
1. Introduction to LC/MS-overview and historical perspective
2. Review of atoms, isotopes, molecules and ions
3. What is LC?-- history, fundamental parameters, columns/solvent systems, concerns related to MS
4. What is MS?-- history, mass analyser types, detectors, vacuum systems; MS/MS and CAD
5. LC/MS Interfaces: historical interfaces, particle beam, atmospheric pressure chemical ionization, electrospray and atmospheric pressure photoionization interfaces
6. Applications review: LC considerations for MS, drugs and metabolites, pharmaceuticals, environmental applications, natural products, protein/peptide analysis
7. Bibliography of LC/MS; glossary of correct and incorrect terms
The Instructors:
Fred Klink is a trainer and consultant to the pharmaceutical, biotech, and chemical industries as well as law enforcement and other government laboratories. Fred’s specialty is HPLC, LC/MS, and solid-phase extraction technologies. Fred has been teaching highly regarded MS and LC/MS courses and providing consulting services since 1996. Fred is the author of several journal articles and book chapters including the LC/MS entry in the Wiley Encyclopedia of Analytical Chemistry.
O. David Sparkman is currently an Adjunct Professor of Chemistry at the University of the Pacific in Stockton, California, where he teaches courses in mass spectrometry and analytical chemistry and manages the mass spectrometry facility. Over the past 28 years, he has developed and taught five different ACS courses in mass spectrometry. He is the author of Mass Spectrometry Desk Reference. He also provides general consulting services in mass spectrometry for a number of instrument manufacturers, manufacturing companies, and government agencies.
To register for this workshop, simply complete the form below: