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Applications

 

Methods

Interlaboratory Tests Demonstrate the Robustness and Transferability of the Toxtyper Workflow

Here we describe a robust and automated research based screening solution for the detection and identification of drugs and drugs of abuse in biological specimens. The workflow was tested with regard to method- and result-transferability from lab to lab.

 

Toxtyper – a Comprehensive LC-MS Screening Solution for Clinical and Forensic Toxicology

Here we describe a robust and automates research based screening solution based on the latest LC-MSn ion trap technology that promises to provide a combination of the highest performance LC-MS/MS and easy-to-use identification with the greatest transferability of results from lab to lab.

 

Authenticity Assessment of Fruit Juices using LC-MS/MS and Metabolomic Data Processing

In this study, the feasibility of LC-MS/MS techniques employing Q TRAP and TripleTOF systems for metabolomic-based authentication of fruit juices (including apple, blueberry, cranberry, grapefruit, orange, pomegranate, and their mixtures) was explored.

 

Enhancing the development of low-emitting products and materials

This Application Note describes how sampling technologies for thermal desorption that are typically used by test laboratories for screening products for chemical emissions can also provide manufacturers with tools that greatly aid the development of low-emitting products and materials, and thus compete in the expanding market for ‘green’ products.

 

Improved Resolution of Triazine Herbicides with Kinetex Core-Shell HPLC/UHPLC Columns and Zebron GC Columns

Environmental laboratories are continuously pushed to deliver lower detection levels and faster sample throughput. A common analysis performed by these labs is triazine herbicides. This analysis can be performed by LC/MS/MS or GC/MS, for which Kinetex core-shell UHPLC/HPLC columns and Zebron GC columns provide resolution and sensitivity improvements as well as time savings.

 

Determination of pesticides by UHPLC-MS

In this application note we present a method combining the rapidness of a UHPLC separation with the advantages of mass spectrometry detection.

 

Targeted and Non-Targeted Screening for Drugs with High Confidence using the AB SCIEX TripleTOF 4600 System and Intuitive Data Processing tools

The high resolution and accurate mass AB SCIEX TripleTOF 4600 LC/MS/MS system was used to screen for drugs from forensic equine urine, and to quantify drug compounds with excellent accuracy and high reproducibility.

 

The Use of Micro Flow UHPLC in Pesticide Screening of Food Samples by LC-MS/MS

Here we present new data using Eksigent ekspert microLC 200 System in combination with a LC-MS/MS method developed on an AB SCIEX QTRAP 4500 system and utilizing the Scheduled MRM algorithm to maximize the number of data points across each peak.

 

The Detection of Allergens in Bread and Pasta by Liquid Chromatography Tandem Mass Spectrometry

A rapid, robust, sensitive and specific LC-MS/MS assay has been developed for the simultaneous detection of four major food allergens peanut, milk, wheat and egg. Peptides of allergens were detected at low parts-per-million (ppm) levels after simple homogenization, digestion with trypsin and SPE cleanup.