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Sample Prep

 

Sample Preparation

 

In this section you'll find a selection of valuable learning materials relating to the use and application of various sample preparation techniques, including technical articles, applications, webinars and eSeminars.

 
 
 
 

Sample Prep Solutions

Sample Prep Solutions #8: Will QuEChERS Work for Me?

QuEChERS (Quick, Easy, Cheap, Effective, Rugged, Safe) is a sample preparation technique used primarily in the food industry to extract and clean up samples for instrumental analysis. Originally, the QuEChERS approach was developed for multi-residue pesticide analysis in fruits and vegetables in 2003 to replace more time-consuming and costly sample preparation techniques.

 

Sample Prep Solutions #7: Ion suppression in Biological Sample Analysis: You May or May Not See It but It’s There

Interferences exist in every chromatographic analysis whether they are recognized or not. Interferences can be visible in your chromatogram and present themselves as reduced peak area counts, split peaks, shoulders around the peak, or peak disappearance. Sample preparation techniques are an effective solution to fix the problems associated with your chromatograms. 

 

Sample Prep Solutions #6: Understanding Your Sample Preparation Options – Why “Mixing and Matching” Should Be In Your Sample Prep Tool Kit

A successful chromatographic analysis starts with the sample. Sample selection, collection, transportation, preservation, storage, and sampling protocol are all aspects of testing that need to be considered in the context of your analytical requirements. 

 
 

Sample Prep Solutions #8: Will QuEChERS Work for Me?

QuEChERS (Quick, Easy, Cheap, Effective, Rugged, Safe) is a sample preparation technique used primarily in the food industry to extract and clean up samples for instrumental analysis. Originally, the QuEChERS approach was developed for multi-residue pesticide analysis in fruits and vegetables in 2003 to replace more time-consuming and costly sample preparation techniques.

 

Sample Prep Solutions #7: Ion suppression in Biological Sample Analysis: You May or May Not See It but It’s There

Interferences exist in every chromatographic analysis whether they are recognized or not. Interferences can be visible in your chromatogram and present themselves as reduced peak area counts, split peaks, shoulders around the peak, or peak disappearance. Sample preparation techniques are an effective solution to fix the problems associated with your chromatograms. 

 

How Solid-Phase Chemistries are Enabling Broader Adoption of SPE in Environmental Applications

Recent separation technology advances, particularly those resulting in more sophisticated analytical instrumentation, have opened new possibilities for environmental monitoring. As analytical technologies improve, laboratories have the ability to identify and quantify harmful toxins and contaminants that had previously gone undetected. However, methods may fall short of unlocking the full potential of newer technologies, including LC–MS–MS and GC–MS, if they do not adopt advanced sample preparation techniques in parallel. Environmental laboratories face unique challenges compared to other industries, such as pharmaceutical discovery or toxicology. 

 
 

Enhancing the development of low-emitting products and materials

This Application Note describes how sampling technologies for thermal desorption that are typically used by test laboratories for screening products for chemical emissions can also provide manufacturers with tools that greatly aid the development of low-emitting products and materials, and thus compete in the expanding market for ‘green’ products.

 

The Use of Micro Flow UHPLC in Pesticide Screening of Food Samples by LC-MS/MS

Here we present new data using Eksigent ekspert microLC 200 System in combination with a LC-MS/MS method developed on an AB SCIEX QTRAP 4500 system and utilizing the Scheduled MRM algorithm to maximize the number of data points across each peak.

 

Determination of Bisphenol A in Drinking Water

A comprehensive sample preparation and analytical procedure was developed for determining BPA in drinking water. This fast procedure employed materials and techniques selected in part for speed, but also those that would not contribute unwanted artifacts.

 
 

Automated Sample Preparation using the Agilent 7696A WorkBench

Presenter: Dr Frank David (R&D Manager, Research Institute for Chromatography [RIC])
In collaboration with: Agilent Technologies

ON-DEMAND

Sample preparation is one of the major bottlenecks in an analytical workflow. Modern labs are continuously looking for automation, reduction of solvent consumption, safety and unattended operation. This webinar shows how the Agilent 7696 Workbench can significantly contribute to these goals.

 

Revisiting the Advantages of the QuEChERS Approach to Sample Preparation

Presenter: Steven Lehotay 
In collaboration with Supelco

ON-DEMAND

The “quick, easy, cheap, effective, rugged, and safe” (QuEChERS) approach to sample preparation is very flexible and has many options for analysis of a diverse range of organic chemicals in different matrices. This presentation will describe those options and the reasons for the choices made depending on the range of analytes and matrices being tested.

 
 

View the on-demand presentations including:

Automated Malt Analysis using Discrete Analyzers
by Aaron McLeod

Direct Analysis of Food and Beverages using SPME-GC-MS/MS - No Sample Cleanup, Automated and Highly Specific
by Elena Ciceri

HPAE-PAD for Prebiotic Ingredient Characterizations
by Parul Angrish & Manali Aggrawal

Applying ICP-MS to Speciation and Quantitative Analysis of Arsenic in Foodstuffs and Beverages
by Antonio Signes-Pastore & Simon Nelms

Revisiting the Advantages of the QuEChERS Approach to Sample Preparation

Presenter: Steven Lehotay 
In collaboration with Supelco

ON-DEMAND

The “quick, easy, cheap, effective, rugged, and safe” (QuEChERS) approach to sample preparation is very flexible and has many options for analysis of a diverse range of organic chemicals in different matrices. This presentation will describe those options and the reasons for the choices made depending on the range of analytes and matrices being tested.