PFAS testing spans water, soil, biosolids, and tissue, each with contamination risks and matrix effects. EPA 1633 pushes labs to reach ultra-trace limits while keeping blanks clean and instruments stable. Food samples raise the challenge further, as fats and proteins can quickly overwhelm LC-MS/MS systems.
This eBook guides readers through five chapters: method development and QC, applications in water, solids, and tissue, and a stress test with food matrices. Each section highlights choices in prep, cartridge design, and automation, supported by QC and proficiency data. Together, these insights give bench scientists a structured view of how to carry EPA 1633 workflows into everyday lab practice.
What you will learn:
- Practical steps for applying EPA 1633 LC-MS/MS to 40 PFAS targets.
- Why cartridge design and automated SPE reduce matrix noise and improve recovery.
- Techniques for distinguishing linear from branched isomers in complex samples.
- The role of QC and proficiency testing in demonstrating method performance.
- How data from food extracts confirm signal stability across extended runs.
