Home / Bioclinical / Blog

Bioclinical Analysis

Separation Science Bioclinical offers free learning from the experts covering methods, applications, webinars, eSeminars, videos, tutorials for bioclinical analysis, forensic analysis and toxicology users of chromatography, mass spectrometry, sample preparation and related analytical techniques.

Featured Educational Resources

Quantitation of Selected PFAS in Human Whole-Blood Utilizing VAMS (Volumetric Absorptive Micro Sampling) and Latest-Generation Triple Quadrupole Instrumentation

19 October, 2021

Andrew Patterson (Eurofins Environment Testing America - Specialty Services Division)

This webinar provides an effective approach for studying PFAS in human whole blood and also discusses the challenges of PFAS analysis in blood serum and how to overcome them.

LESS IS MORE: Microelution Extraction for High Throughput Bioanalytical Workflows

On-demand

Stephanie Marin (Biotage LLC, Charlotte, NC, USA)

By watching this presentation you learn to appreciate the differences between microelution and traditional SPE products and protocols, describe processing conditions for manual and automated workflows for microelution columns, and compare protocols and results for a panel of steroids and a drug panel using traditional SPE columns and microelution columns.

Perfecting Pcats – Developing a More Robust UHPLC-MS/MS Method for Plasma Catecholamines using Low Volume SPE

On-demand

Adam Senior (Biotage GB Limited)

This presentation discusses typical plasma matrices and the effects of different sample pre-treatments. The importance of analyte and sorbent pH control is discussed along with selection of suitable approaches to maximize removal of matrix interferences and enhance method robustness. The final section covers different strategies for analyte enrichment to maintain method LOQs, using manual and automated low volume elution SPE procedures.

NPS Screening and Identification: Nominal and Accurate Mass Approaches for Ultimate Success

On-demand

Pierre Negri (SCIEX)

In this webinar, the presenter discusses how nominal mass and accurate mass instruments can be used in forensic toxicology workflows as two different yet complementary approaches for screening and identifying novel psychoactive substances (NPS). The two different LC-MS/MS platforms are presented with an explanation of how they are used strategically for the detection and identification of NPS with a high level of sensitivity and specificity.

Extraction of New and Emerging Drugs of Abuse Prior to LC-MS or GC-MS Analysis

On-demand

Jillian Neifeld (Biotage AB)

This webinar discusses how to extract various designer drugs of abuse from urine, whole blood, oral fluid, and hair prior to LC-MS or GC-MS analysis. Specifically discussed are synthetic cannabinoids, synthetic opioids, synthetic benzodiazepines, and synthetic stimulants.

Trials and Tribulations of Fat Soluble Vitamin Analysis by UHPLC-MS/MS

On-demand

Alan Edgington (Biotage, UK)

This webinar summarizes the work performed to develop a method for the analysis of fat-soluble vitamins including vitamins A (Retinol and Beta Carotene), D (25 Hydroxy D3 and 25 Hydroxy D2), E (Alpha Tocopherol) and K (Phylloquinone and Menaquinone) in human serum.

Smarter Sample Prep: Moving your Workflow from Manual Processing to Automation

On-demand

Dr Dan Menasco (Biotage AB)

This webinar discusses the systems and software available to address various levels of sample complexity and the transitional elements one must consider to strategically move into automating sample prep.

One Size Does Not Fit All: Considerations for Minimizing Matrix Effect and Maximizing Recovery for Clinical Panels Large and Small

On-demand

Dr Lee Williams (Biotage GB Limited)

This webinar discusses typical clinical matrices such as whole blood, plasma, serum, urine and oral fluid with specific emphasis on a variety of endogenous components. Matrix complexity will be illustrated and related to a variety of clinical assays, demonstrating potential impact on method robustness.

Opioids: Choosing the Best Solution for your Laboratory

On-demand

Jillian Neifeld (Applications Chemist, Biotage)

This webinar provides sample preparation solutions for synthetic opioids analysis in forensic laboratories. We discuss the opioid epidemic, extraction techniques to include supported liquid extraction and solid phase extraction, matrices that can be analysed with these techniques, as well as results obtained from the various extraction types.

New Perspectives and Technology in Pyrolysis GC-MS for Forensic and Polymer Analysis: How Smart-Ramped Pyrolysis Leads to Improved Data

On-demand

Kurt Thaxton (GERSTEL International Product Manager, Pyrolysis and Thermal Desorption)

This introductory webinar will describe the hardware advances in pyrolysis-GC-MS in more detail and provides examples of improvement in data quality, using samples drawn from forensic and polymer application areas.

Advances in Forensics & Toxicology eSeminar

On-demand

Tania A. Sasaki, Alex J. Krotulski, Rafael Venson, Fred Foster, Alberto Salomone & Timothy Fassette

This on-demand eSeminar sponsored by GERSTEL, SCIEX and UCT, covers topics such as drug testing of urine, pharmaceutical and drugs of abuse monitoring, designer drug detection, sample preparation techniques for opioids, and QuEChERS in DUI testing.

High Resolution Orbitrap MS for Detecting New Psychoactive Drugs, A User’s Perspective

On-demand

Marta Concheiro (Assistant Professor of Forensic Toxicology, John Jay College of Criminal Justice, City University of New York)

In this webinar you will learn about two analytical methods for the determination of new psychoactive stimulants in urine by liquid chromatography–high resolution mass spectrometry with Orbitrap technology.

Detección de las Nuevas Sustancias Psicoactivas mediante el espectrómetro de masas de alta resolución Orbitrap MS, perspectiva del usuario

A pedido

Marta Concheiro (Profesora Asistente de Toxicología Forense, John Jay College of Criminal Justice, City University de Nueva York)

En este seminario web aprenderá en el español sobre dos métodos analíticos para la determinación de nuevos estimulantes psicoactivos utilizando cromatografía liquida acoplada a espectrometría de masas de alta resolución con tecnología de Orbitrap™ MS.

The power of CE-MS: Charge Heterogeneity Analysis

On-Demand Webinar

Esme Candish (SCIEX)

Integrating CE and electrospray ionization (ESI) into one dynamic process, within the same device (CESI), simplifies coupling CE with MS. CESI-MS can be employed to characterize differences in the charge and glycosylation profiles of mAbs from different manufacturers. Learn the value of CESI-MS to the characterization of mAbs, and how the technique can characterize differences in charge and glycosylation profiles.

Introduction to CE Online Learning

Self-paced Online training

Analytical Training Solutions

Each course on Analytical Training Solutions has been divided into a number of modules, with each module focusing on one particular aspect of the overall course. The modules have been created in a logical manner, and by starting with the first module and working through them in the order provided creates the best learning environment for the user. In addition, as each course is divided into modules it is then very simple to find a particular section again in the future; for example, if you want a recap on a particular subject.

FREE learning from the experts!

Subscribe to the Bioclinical Analysis eNewsletter.



Follow us on Twitter: @Sep_Science

Latest Blog Posts