Biopharma Impurities

Discover tools for detecting impurities in biopharmaceuticals.

A laboratory flask on a bench contains culture media that glows with a blue neural network pattern, surrounded by holographic projections of molecular structures and data streams, representing AI-driven media development in a modern biotech lab.
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Expert insights from Jake Bell on how advanced separation science, AI, and robotic automation are tackling a significant biomanufacturing bottleneck: scalable, animal-free culture media.
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From ampholyte gradients to icIEF, discover how capillary isoelectric focusing separates proteins by isoelectric point for high-resolution biopharmaceutical analysis.
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Explore sterility assurance methods, including closed-loop sampling systems and aseptic transfer for contamination-free lab environments.
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This guide explains how analytical scientists use chemometric models for mass spectrometry—and tools such as SIMCA—to interpret complex datasets with confidence.
3D rendering illustrating mass transfer kinetics in a core-shell column. GLP-1 peptide ribbons (blue/green) interact with the porous shell stationary phase but are blocked by the solid silica core, minimizing the Van Deemter C-term contribution.
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Core-Shell Particle Technology for Peptide Work: Mechanisms for Improving Resolution in GLP-1 Analysis

Conceptual illustration of size exclusion chromatography applications, showing large blue antibody molecules separating from smaller orange fragments as they flow through porous beads in a column.
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Applications of Size Exclusion Chromatography in Biopharma, Food, and Polymer Analysis

Two unlabeled injection pens resting on a stainless steel laboratory bench, representing the finished product samples that undergo rigorous GLP-1 peptide impurity profiling.
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GLP-1 Peptide Impurity Profiling: Separating D-Isomers, Oxidation States, and Truncations

Test tube row. Concept of medical or science laboratory, liquid drop droplet with dropper in blue red tone background.
Application Notes

Reactions, Reactions, Reactions -  Data Automation to The Rescue!

Separation Science Placeholder Image
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Advancing GLP-1 Peptide Analysis: Chromatography Challenges and Innovations

Close-up of pharmaceutical vials moving through an automated filling and sealing machine, representing the critical quality control environment for PFAS and E&L testing.
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Bridging the PFAS Oversight Gap: Advanced LC-HRAM-MS Strategies for E&L Testing

3D-rendered antibody structure in a colorful biological environment, representing molecular interactions targeted by protein affinity columns in biopharmaceutical analysis.
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New Affinity Column Simplifies Antibody Titer and Aggregate Analysis Workflows

3D rendering of tangled blue protein structures on a black background, representing formations observed during protein aggregates analysis.
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Protein Aggregates: Analytical Techniques to Address Hidden Complexities

Learning Hubs

Optimize Peptide Drug Development with Smarter LC-MS Strategies

Shows & Conferences

PREP 2024: Explore the Cutting-Edge of Chromatography in Philadelphia