Impurity Analysis

Explore methods for detecting and quantifying impurities in small and large molecules.

A digital illustration of oligonucleotides flowing through a futuristic chromatography column, where a glowing blue energy field representing controlled retention factor actively organizes chaotic, tangled strands into distinct, resolved bands, symbolizing the separation of impurities.
ArticlesData-driven method development and 2D-LC reveal the hidden role of retention factor, pressure, and pore size in oligonucleotide separations.
ArticlesThis guide explains how analytical scientists use chemometric models for mass spectrometry—and tools such as SIMCA—to interpret complex datasets with confidence.
ArticlesSuperficially porous particles are transforming peptide impurity profiling. This article applies the Van Deemter theory to explain how core-shell columns improve peak capacity, sensitivity, and robustness in GLP-1 separations.
Webinars
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Discover how preparative LC can streamline your analytical workflows for compound purification.