Column Selection for Endocrine Testing by LC-MS/MS

Optimize endocrine testing using LC-MS/MS. Learn about key considerations and the latest advancements in column technology.

| 1 min read

byAimee Cichocki and Stephanie Marin

In the ever-evolving field of endocrine testing by LC-MS/MS, the choice of chromatographic column can significantly impact the accuracy and reliability of results. Separation Science recently had the pleasure of interviewing Dr. Stephanie Marin, the Global Clinical Market Development Manager at Phenomenex, to delve into this critical aspect of assay development.

With over a decade of experience in clinical assay validation and a deep expertise in liquid chromatography and mass spectrometry, Dr. Marin offers invaluable insights into the nuances of column selection for endocrine testing. In this conversation, she addresses key considerations, from the importance of looking beyond traditional C18 columns to the latest advancements in column technology that are shaping the future of endocrine analysis.

In this interview, Dr. Marin responds to the following questions:

Could you provide a brief overview of the various column chemistries available for endocrine testing by LC-MS/MS?
Why is it important to look beyond just a C18 column for endocrine testing?
What are the main factors that researchers should consider when selecting a column for endocrine testing?
Are there any particular column chemistries that you would recommend for specific types of endocrine compounds?
Have there been any recent advancements in column technology that are particularly beneficial for endocrine testing?

Share Your Expertise! Would you like to share your knowledge and news with the broader analytical community? Sign up to our contributor list today!

Meet the Author(s):

Aimee Cichocki
Aimee Cichocki is the Managing Editor at Separation Science and Chromatography Forum. Aimee brings a broad range of experience in creating, editing, and formatting scientific content. With a degree in medicinal chemistry, a 10-year background in formulation chemistry, an MBA, and a diverse background in publishing, Aimee guides editorial initiatives at Separation Science and Chromatography Forum. Aimee is dedicated to ensuring the delivery of informative, reliable, and practical content to our audience of analytical scientists.
Stephanie Marin
Stephanie J. Marin, Ph.D. is the Clinical and Forensics Global Market Development Manager at Phenomenex. She received her Ph.D. in chemistry from Arizona State University. She has expertise in sample preparation, liquid chromatography, and mass spectrometry, and has over 10 years of experience developing and validating clinical assays from her tenure at the ARUP Institute for Clinical and Experimental Pathology. Dr Marin has worked in LC product and applications development at Hamilton Company and Selerity Technologies, in analytical services for Rohm and Haas (now Dow) and was a supervisor at an EPA certified laboratory. Before joining Phenomenex, Stephanie was a Senior Applications Chemist at Biotage. She is the author of over 30 peer reviewed publications and book chapters and over 100 abstracts presented at national and international meetings.

Here are some related topics that may interest you:

Loading Next Article...