Purification chemists typically screen preparative LC phases primarily for selectivity to achieve target resolution. But that initial phase selection also locks in alkaline wash limits. It simultaneously dictates expected fraction volumes and long-term column lifetime.
This resource details how hybrid silica particle technology combines target selectivity with mechanical and chemical stability.
Download this technical guide to:
- Evaluate peak shape and retention stability across 300 alkaline cleaning cycles with 0.1 M NaOH
- Trace a scale-up case study demonstrating smaller fraction volumes and a 40% reduction in overall costs for insulin purification
- See analytical-to-preparative scalability with matched purity and yield from 3 to 10 µm particle sizes
Plus access the bonus content:
- [Technical Note] Packing Properties of YMC-Triart Prep
This technical note shows how, even after the exposure to 50–100 MPa (500–1000 bar), the YMC-Triart Prep material shows no signs of degradation. While conventional silica creates problematic fines that clog systems and increase pressure, YMC-Triart Prep maintains consistent performance cycle after cycle. It's perfect for pharmaceutical labs demanding reliability and efficiency in their preparative workflows, and is the ideal choice for any preparative chromatography application. - [Brochure] YMC-Triart Columns
This brochure gives a snapshot of the phases including particle sizes, pore sizes, carbon load and recommended limits, as well as the Tanaka values.
