Targeted MS/MS methods provide sensitive, reliable quantitation for known pesticides. However, predefined acquisition methods can miss compounds outside the target list. High-resolution mass spectrometry (HRMS) captures a broader chemical profile, helping laboratories detect expected analytes, investigate unknowns, and preserve data for future analysis.
This infographic compares targeted MS/MS with untargeted HRMS and explores the evidence used to identify unknown pesticides, including exact mass, isotopic patterns, and fragment matching. It also shows how laboratories can revisit archived data when new pesticide threats emerge, reducing the need to re-extract or reanalyze samples.
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