HPLC 2026 Heads to Indianapolis

Indianapolis, IN | June 6–11, 2026

The 55th International Symposium on High Performance Liquid Phase Separations and Related Techniques takes place June 6–11, 2026 at the JW Marriott Indianapolis, marking the first time in over 30 years that the symposium has returned to the American Midwest.

Industrial Focus Shapes the Program

Indianapolis anchors a substantial pharmaceutical manufacturing corridor. Eli Lilly's headquarters sits blocks from the conference venue, and the broader Midwest supports a density of biotech and contract manufacturing operations that feed directly into the program's emphasis on practical separations work.

The Applications track of HPLC 2026 addresses workflows that have moved from exploratory research into production: ADC characterization, oligonucleotide recovery optimization, and mRNA-related methods that regulatory agencies have yet to standardize. These sessions draw presenters from both academic labs and production facilities who have already navigated the gap between proof-of-concept and validated method.

Predictive Tools Enter Method Development

Machine learning approaches to retention prediction and gradient optimization now appear in mainstream method development. The Fundamentals track examines closed-loop systems that reduce solvent consumption by handling iterative optimization computationally before any mobile phase moves through the column. For labs facing green chemistry mandates or simple cost pressure, these tools shift the burden of trial-and-error from the bench to the software.

Short Courses and Submission Deadlines

Pre-conference short courses run June 6–7, covering topics from UHPLC troubleshooting to chemometrics and advanced method optimization. The preliminary program is scheduled for release March 16.

Oral abstract submissions have closed, but poster submissions remain open through March 30. Poster sessions at the HPLC symposium tend toward working discussions rather than formal presentations, and often generate the most direct problem-solving exchanges of the week.

Key Dates

March 16: Preliminary program published
March 30: Poster abstract deadline
April 13: Early-bird registration closes
April 27: Registration deadline for presenting authors
June 6–7: Short courses
June 8–11: Main symposium

Exhibition and Networking

The exhibition hall operates alongside the scientific program, with instrument manufacturers, software vendors, and consumables suppliers presenting current platforms. For teams evaluating analytical capabilities or benchmarking existing instrumentation, the symposium consolidates comparison opportunities that would otherwise require months of individual demonstrations.

The JW Marriott connects directly to the Indiana Convention Center via skywalk, with the exhibition and meeting spaces concentrated in over 100,000 square feet of contiguous venue.

Registration

Early-bird rates apply through April 13. Bundled packages include meeting registration, gala dinner, and a half-day short course. Full-day courses are available at additional cost.

Registration and program details: hplc2026-symposium.org