This technical article provides details regarding phase dewetting or phase collapse in an HPLC column.
Phase dewetting in HPLC is the same process we used to call phase collapse. Although often drawn to look like a tennis ball with stationary phase with the C18 groups as fuzz on the surface, the particles used to pack a C18 column are totally porous, resembling a rigid sponge. Nearly all of the surface area of such particles is inside the pores. The particles are typically used for small molecule separations.
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