Home / MS / Blog

Mass Spectrometry

Separation Science offers free learning from the experts covering methods, applications, webinars, eSeminars, videos, tutorials for MS analysis users of chromatography, mass spectrometry, sample preparation and related analytical techniques.

Featured Educational Resources

Latest Mass Spectrometry-based Trends for Identifying and Quantifying Unknown PFAS Compounds

13 November, 2019

Lee Ferguson & Abigail Joyce (Duke University, North Carolina, USA)

In this webinar, leaders of the Ferguson Laboratory will discuss a Thermo Scientific™ Orbitrap™ Mass Spectrometer-based method, which captures more meaningful data to demystify unknown PFAS compounds. Additionally, a triple-quadrupole MS method will be discussed, which achieves desired limits of detection for identified PFAS compounds.

Dealing with Metal Adduct Ions in Electrospray: Part 1

Fundamentals of MS

In this article we will be discussing specifically the adduction of alkali metal ions (Na, K), to analyte molecules and will therefore use the term “metal adduct ion” to refer to these species.

Dealing with Metal Adduct Ions in Electrospray: Part 2

Fundamentals of MS

Previously we discussed the fundamental issue of metal adduct ion formation in electrospray LC/MS including method development strategies for dealing with adduct ions. This article will examine a real-world application which employs these strategies.

Adjusting Electrospray Voltage for Optimum Results

Fundamentals of MS

An electrospray LC/MS interface consists of an enclosed, atmospheric pressure chamber. The HPLC effluent enters this chamber through a capillary tube which is surrounded by a second, concentric tube through which a nebulizing gas is applied. Learn how you can optimise your methods by adjusting the electrospray voltage.

Improving Electrospray LODs by Decreasing Column Diameter

Fundamentals of MS

Reducing the internal diameter of your HPLC columns is an advantage for electrospray (ESI) LC/MS users. To understand this, two characteristics of ESI must be understood: (1) how response (i.e., peak area or height), is related to analyte concentration and (2) how response varies with HPLC flow rate.

LC-MS/MS for Chromatographers and GC-MS for Operators and Method Developers

Self-paced online training

Analytical Training Solutions

Each course on Analytical Training Solutions has been divided into a number of modules, with each module focusing on one particular aspect of the overall course. The modules have been created in a logical manner, and by starting with the first module and working through them in the order provided creates the best learning environment for the user. In addition, as each course is divided into modules it is then very simple to find a particular section again in the future; for example, if you want a recap on a particular subject.

FREE learning from the experts!

Subscribe to the Mass Spectrometry eNewsletter with daily, weekly or monthly updates.

Be part of the conversation and join The Chromatography Forum.

Follow us on Twitter: @Sep_Science

Latest Blog Posts