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Separation Science offers free learning from the experts covering methods, applications, webinars, eSeminars, videos, tutorials for MS analysis users of chromatography, mass spectrometry, sample preparation and related analytical techniques.

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Featured Educational Resources

Turn your Triple Quad up to 11!


April Quinn-Paquet (Technical Product Manager, SCIEX)

You will learn about the latest features for acquisition in SCIEX OS software including automatic data processing and decision rules, which can automatically perform actions on the queue according to user-specified criteria.

Precise Testing of Pesticides in Food using the SCIEX 7500 System


Jianru Stahl-Zeng (Global Technical Leader for Food and Environmental, SCIEX)

This presentation gives an overview of the new SCIEX 7500 System that is integrated with innovative technologies. The presenter showcases the capabilities and potential of the SCIEX 7500 System for precise pesticide testing in food.

Dilution and Sensitivity: Effects on a Food Contaminant Mega-Method


Dr Robert Di Lorenzo (Global Technical Marketing, Food & Beverage, SCIEX)

This presentation explores how far we can push dilution while still meeting sensitivity requirements to simplify sample preparation and analysis workflows. With the SCIEX Triple Quad™ 7500 LC-MS/MS System– QTRAP® Ready, a single mega-method comprising hundreds of pesticides, veterinary drugs and mycotoxins will be analyzed from various food and feed matrices from a single sample preparation method.

Understanding the Benefits of Triple Quadrupole ICP-MS in Everyday Analysis


Daniel Kutscher and Magda Mandic (Thermo Fisher Scientific)

This webinar highlights new opportunities where triple quadrupole ICP-MS will allow you to improve performance and efficiency, but also return on investment. It is demonstrated that modern TQ-ICP-MS systems are as easy to install and operate as a single quadrupole instrument.

Trials and Tribulations of Fat Soluble Vitamin Analysis by UHPLC-MS/MS


Alan Edgington (Biotage, UK)

This webinar summarizes the work performed to develop a method for the analysis of fat-soluble vitamins including vitamins A (Retinol and Beta Carotene), D (25 Hydroxy D3 and 25 Hydroxy D2), E (Alpha Tocopherol) and K (Phylloquinone and Menaquinone) in human serum.

Key Notes on Citing Spectral Library Searches

Letter to the Editor

O. David Sparkman

A collection of mass spectra of known compounds and the program used to search a spectrum of an unidentified compound are two different entities. The results obtained depend on both. Full and correct citations should be the norm - find out how to do this correctly.

Introduction to and Practical Applications of the SCIEX Triple Quad 7500 LC-MS/MS System – QTRAP Ready


Ian Moore and Jianru Stahl-Zeng (SCIEX)

Learn how the SCIEX 7500 System enables you to attain up to 7X greater sensitivity to quantify more trace analytes at lower levels across a broad suite of sample types and workflows.

Elemental Analysis of e-Cigarettes: Pushing the Boundaries of ICP-MS Analysis to a New Level


David Fishwick (Broughton Nicotine Services, UK) and James Hannan (Thermo Fisher Scientific, UK)

This presentation will focus on trace elemental analysis associated with the growing industry of Electronic Nicotine Delivery Systems (ENDS), more commonly referred to as e-cigarettes, using ICP-MS. It will cover the development of robust methods for this analysis using both single and triple quadrupole ICP-MS technology.

Towards AI-Powered Cost Effective Elemental ICP-OES Analysis


Eric Vanclay and Lindsey Whitecotton (Agilent)

In this ICP-OES webinar the presenters showcase how artificial intelligence based smart tools paired with innovative sample introduction systems can reduce sample remeasurement to improve productivity and overall performance, and simplify routine maintenance.

Trace Metals Analysis in Dietary Supplements Using ICP-MS: How to Achieve Regulatory Compliance and Minimize Contamination


Grant Fulford and Hans Krueger (Eurofins Food Integrity and Innovation)

This presentation covers ICP-MS analysis of dietary supplements for trace metals and minimizing contamination to meet regulatory compliance. Case studies and data are presented to show the challenges that regulations for trace metals can present in ICP-MS analysis of food and dietary supplements.

Perform like a PRO: Robust ICP-OES analysis with the new iCAP PRO Series ICP-OES


Dr Sukanya Sengupta & Nora Bartsch (Thermo Fisher Scientific)

A technique of choice for elemental analysis is inductively coupled plasma-optical emission spectroscopy (ICP-OES), which is ideally suited for a range of sample types. However, some samples present analytical challenges including high matrix samples and samples which produce complex spectrum impacting accuracy. Watch this presentation to find out how the latest ICP-OES technology can address these issues and improve your elemental analysis.

Latest Mass Spectrometry-based Trends for Identifying and Quantifying Unknown PFAS Compounds


Lee Ferguson and Abigail Joyce (Duke University, North Carolina, USA)

In this webinar, leaders of the Ferguson Laboratory discuss a Thermo Scientific™ Orbitrap™ Mass Spectrometer-based method, which captures more meaningful data to demystify unknown PFAS compounds. Additionally, a triple-quadrupole MS method will be discussed, which achieves desired limits of detection for identified PFAS compounds.

How to Easily Analyse Petrochemical Samples by ICP-OES


Matthew Cassap (Thermo Fisher Scientific)

Petrochemical samples present a number of different challenges when analyzing for trace elements by ICP-OES, these include the stable introduction of the sample in to the plasma, the complex matrix and potential interferences. This webinar describes these challenges and how to easily overcome them, by the development of robust methods that produce excellent results.

Dealing with Metal Adduct Ions in Electrospray: Part 1

Fundamentals of MS

In this article we will be discussing specifically the adduction of alkali metal ions (Na, K), to analyte molecules and will therefore use the term “metal adduct ion” to refer to these species.

Dealing with Metal Adduct Ions in Electrospray: Part 2

Fundamentals of MS

Previously we discussed the fundamental issue of metal adduct ion formation in electrospray LC/MS including method development strategies for dealing with adduct ions. This article will examine a real-world application which employs these strategies.

Adjusting Electrospray Voltage for Optimum Results

Fundamentals of MS

An electrospray LC/MS interface consists of an enclosed, atmospheric pressure chamber. The HPLC effluent enters this chamber through a capillary tube which is surrounded by a second, concentric tube through which a nebulizing gas is applied. Learn how you can optimise your methods by adjusting the electrospray voltage.

Improving Electrospray LODs by Decreasing Column Diameter

Fundamentals of MS

Reducing the internal diameter of your HPLC columns is an advantage for electrospray (ESI) LC/MS users. To understand this, two characteristics of ESI must be understood: (1) how response (i.e., peak area or height), is related to analyte concentration and (2) how response varies with HPLC flow rate.

LC-MS/MS for Chromatographers and GC-MS for Operators and Method Developers

Self-paced online training

Analytical Training Solutions

Each course on Analytical Training Solutions has been divided into a number of modules, with each module focusing on one particular aspect of the overall course. The modules have been created in a logical manner, and by starting with the first module and working through them in the order provided creates the best learning environment for the user. In addition, as each course is divided into modules it is then very simple to find a particular section again in the future; for example, if you want a recap on a particular subject.

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