Content by Cytiva

Science technology concept. Scientist. Scientific experiment.
BlogsSize exclusion chromatography is a powerful technique for obtaining reliable information on size of biomolecules under native conditions. A white paper presenting fundamentals about analytical SEC and describing how new-generation agarose-based SEC columns are used in analysis of biomolecules.
BlogsIn the characterization of protein hydrolysates, it is important to analyse the size distribution. This is challenging with techniques such as RPC, or with SDS-PAGE as small peptides are not separated efficiently according to size.
BlogsScreening for mAb aggregation is important in the production of mAb. When performing aggregate analysis on mAbs there is often no issue when the aggregate level is above 1%.
BlogsWith analytical SEC, tendency to aggregate and other size changes can be studied under different conditions, such as in storage stability analyses of biopharmaceuticals.