Content by Cytiva

BlogsSize exclusion chromatography is a powerful technique for obtaining reliable information on size of biomolecules under native conditions. A white paper presenting fundamentals about analytical SEC and describing how new-generation agarose-based SEC columns are used in analysis of biomolecules.
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BlogsIn the characterization of protein hydrolysates, it is important to analyse the size distribution. This is challenging with techniques such as RPC, or with SDS-PAGE as small peptides are not separated efficiently according to size.
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BlogsScreening for mAb aggregation is important in the production of mAb. When performing aggregate analysis on mAbs there is often no issue when the aggregate level is above 1%.
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BlogsWith analytical SEC, tendency to aggregate and other size changes can be studied under different conditions, such as in storage stability analyses of biopharmaceuticals.
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