Learning Hubs

Size-Exclusion Chromatography Resource Hub

Your one-stop shop for everything SEC, with a focus on monoclonal antibodies.
Six-part tutorial series with quiz and certificate of completion.

Want to brush up on your size-exclusion chromatography knowledge? Browse a library of information specifically curated to provide a strong foundation on SEC.

Access tutorials, application notes, guides, and more. Explore an in-depth series of SEC learning modules for a certificate of completion or strengthen your knowledge within specific application areas with a variety of application notes.


Videos: Past Present and Future of SEC


Think Differently: A Brief Background on SEC




Overcoming SEC Challenges





Designing the Next Generation of SEC Columns



Guides



Guide to SEC Optimization




Application Notes


Faster SEC-UV Analyses of mAb HMWS




Improved Separation Performance of Monoclonal Antibody and Antibody Drug Conjugates




Expanding Size-Exclusion Chromatography Platform Method Versatility for Monoclonal Antibody Analysis



A New Benchmark in Inert SEC Column Design








Evaluation of SEC-MALS Data Quality with Premier Protein SEC Columns 







The available tutorials in this course include:

  • [Part 1] Analytical Challenges and Use of SEC for mAbs
  • [Part 2] Principles and Practice of SEC for Reliable Monoclonal Antibody Analyses
  • [Part 3] Selecting Appropriate SEC Pore Size for Reliable Protein / Peptide Separations
  • [Part 4] Choosing Appropriate SEC Column Size based on LC System and Application Goals
  • [Part 5] Considerations to Maximize SEC Column Life
  • [Part 6] Developing Robust SEC Methods for Protein Size Variants

The Presenter:

Bill Warren
Principal Product Manager, Waters

Bill received his Master’s in Microbiology and Immunology from the University of Louisville School of Medicine. In 1986, he joined Waters Corporation as a senior applications chemist involved with the research and development of HPLC, FPLC, and Capillary Electrophoresis applications for the analysis and purification of proteins, peptides, and nucleic acids. Bill is currently a Principal Bioseparation Columns Product Manager whose responsibilities involve assisting in the development and commercialization of innovative reagents and chromatography-based technologies for the separation, purification, and characterization of biological molecules

Sponsor:

Sponsor(s):

  • Waters logo