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The Function of GC Columns

A general overview of the purpose of GC columns, key processes involved and a description of differences between them.
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byMatthew Klee
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This technical article provides a general overview of the purpose of GC columns, key processes involved and a description of differences between them.

The column is the heart of the gas chromatograph. It is through interactions between solutes (individual compounds in the sample, also called analytes) and the stationary phase within the column that separation can occur. The driving force that moves solutes forward, the mobile phase, is a gas, also called the carrier gas. Unlike in liquid and supercritical fluid chromatographies, the mobile phase in GC plays no active role in the separation process other than to move solutes toward the column outlet.

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Meet the Author(s):

  • Matthew Klee

    Dr Matthew S. Klee is internationally recognized for contributions to the theory and practice of gas chromatography. His experience in chemical, pharmaceutical and instrument companies spans over 30 years. During this time, Dr Klee’s work has focused on elucidation and practical demonstration of the many processes involved with GC analysis, with the ultimate goal of improving the ease of use of GC systems, ruggedness of methods and overall quality of results. 

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