Articles

A professional scientific visualization blending a photorealistic HPLC column apparatus with a glowing 3D molecular graph and abstract neural network data paths, illustrating computational foresight in separation science.
Articles

Machine Learning for Retention Time Prediction in LC: What the Models Can Actually Do

Separation scientist reviewing AI-assisted chromatography software predicting retention times and peaks, illustrating AI tools for separation science workflows
Articles

AI and Machine Learning in Analytical Science: A Practical Guide for Separation Scientists

Industrial landscape with fuel processing plant and mountainous background
Articles

How Multidimensional Separations and AI are Deciphering the World’s Most Complex  Chemical Feeds

Illustration of metabolites represented as bubbles
Articles

Improving Confidence in LC-MS/MS Metabolite Identification

LC-MS characterization of GLP-1 agonists showing a multiply charged electrospray envelope deconvoluted to an intact mass.
Articles

LC-MS Characterization of GLP-1 Agonists: Ionization and Data Interpretation

GLP-1 related substance testing and regulatory review of synthetic peptide impurities against ICH and FDA thresholds.
Articles

GLP-1 Related Substance Testing: Regulatory Considerations for Synthetic Peptide Impurities

Ion-pairing chromatography of GLP-1 and charged peptides showing a separation tuned by perfluorinated acid reagents.
Articles

Ion-Pairing Chromatography for GLP-1 and Charged Peptides

Reversed-phase HPLC column selection and mobile phase for GLP-1 peptide analysis.
Articles

Reversed-Phase HPLC for GLP-1 Peptides: Column Selection and Mobile Phase

Scientist developing a UHPLC method for GLP-1 impurity profiling, optimizing a gradient on a core-shell column
Articles

GLP-1 Receptor Agonist Impurity Profiling: UHPLC Method Development Guide

Analytical chemist running GLP-1 peptide analysis on a UHPLC system with a chromatogram of resolved impurity peaks.
Articles

GLP-1 Peptide Analysis: Chromatography Methods, Impurity Profiling, and Analytical Challenges

Abstract representation of chromatographic method validation with molecular structures.
Articles

Demystifying Chromatographic Method Validation with John Dolan: Regulatory Guidelines and Lab Best Practices

Laboratory setup for high-performance liquid chromatography (HPLC)
Articles

Chromatography Basics with John Dolan: Core Parameters and System Suitability