Sunscreen Safety – Introducing a new Certified Reference Material Mix for Furocoumarins

by | Environmental, Food & Beverage, Liquid Chromatography

In this article from Issue 11 of the Analytix Reporter, produced by Merck, the safety of sunscreens is under scrutiny and a new certified reference material mix for furocoumarins introduced to alleviate the worry associated with their potential presence in sunscreens.


Furocoumarins are a class of chemical compounds produced by a wide range of plants, but mostly by the families Apiaceae and Rutaceae. For example, they could be found in citrus oil extracts. Generally, the chemical structure of furocoumarins includes a furan ring, fused with coumarin.

Furocoumarins undergo activation by UV light and can have toxic effects. Therefore, in the EU citrus-derived ingredients of sun-protection and bronzing products must have a furocoumarin content of below 1 mg/kg. The International Fragrance Association (IFRA) has developed an official analytical method to test for furocoumarins by HPLC-DAD. We offer a certified reference material mix, compliant with the IFRA method.

Key Features

  • TraceCERT® certified reference material traceable to NIST SRM
  • Manufactured following an established workflow according to ISO 17034
  • qNMR certification of each component of the mix (following ISO/IEC 17025 accreditation)
  • Tested for homogeneity and long-term stability using LC method
  • Supplied with a comprehensive certificate including the overall uncertainty

To receive regular copies of the Analytix Reporter eNewsletter provide your email address below:


*The life science business of Merck operates as MilliporeSigma in the U.S. and Canada.

Published  Feb 4, 2022

Home 9 Environmental 9 Sunscreen Safety – Introducing a new Certified Reference Material Mix for Furocoumarins