Welcome to Separation Science

The Challenges of Pesticide Analysis - LC or GC Triple Quadrupole?

20 April, 2021

Bert Popping (FOCOS), Katie Banaszewski (NOW Foods), and Łukasz Rajski (EURL-FV, University of Almería)

This webinar discussion forum, part 1 of the 'Instrument Selection Discussion Series' takes a look at the pros and cons of LC-QqQ and GC-QqQ for the analysis of pesticides in food and agricultural matrices. Industry and technology experts will provide their insights on the various instrumental setups and workflows for analysing real-work samples.

Sample Preparation and Chromatographic Approaches to Quality and Sensory Testing of Beer

22 April, 2021

Klaus Buckendahl (Analytical Sciences Liaison, Advanced Analytical Europe, Merck KGaA, Darmstadt, Germany) and Dr.-Ing. Nils Rettberg (Research Institute for Beer and Beverage Analysis (VLB), Berlin, Germany)

Here you'll hear two presentations, on 'Sample Preparation Tools for Chromatographic Testing of Beer' and 'Flavor Chemistry and Sensory Properties of Non-alcoholic Beer'.

Analysis of PFAS: Strategies to Optimize Performance

12 May, 2021

Detlef Knappe (North Carolina State University, USA), Bradley Clarke (University of Melbourne, Australia) and Carrie McDonough (Stony Brook University, USA)

What analytical approach(es) offer the best results for PFAS in the environment? What are the challenges surrounding adoption of high-resolution mass spectrometry (HRMS) for PFAS analysis? What are the biggest challenges currently in the analysis of PFAS?

Sample Preparation for Fatty and Complex Food Matrices

18 May, 2021

Klaus Buckendahl (Analytical Sciences Liaison, Advanced Analytical Europe, Merck KGaA, Darmstadt, Germany)

In this presentation, sample preparation tools based on zirconia-silica adsorbents for the QuEChERS methodology as well as in form of solid phase extraction (SPE) cartridges will be introduced. Their applicability and improved fat and pigment removal will be demonstrated for pesticide analysis in samples like avocado and spices, as well as for polycyclic aromatic hydrocarbons (PAHs) in edible oils.

Learn New Methods to Enhance Quantitative Workflows for VOC Analysis

On-demand

Hannah Calder (Markes International) and Pascual Pérez Ballesta (European Commission, Joint Research Centre)

In this presentation we introduce the next generation in radial diffusive sampler – the POD Sampler. As part of this webinar you will find out how the POD samplers enhanced design can benefit your analytical workflow and field monitoring campaigns from its creator Pascual Pérez Ballesta.

Atomic Spectroscopy Learning Hub

On-Demand

Gareth Pearson & Eric Vanclay (Agilent)

Improve your analytical skills by visiting the ‘Atomic Spectroscopy Learning Hub’, a free-access portal produced by Separation Science. This portal is designed to enhance your knowledge, best practice and troubleshooting skills in the use of atomic spectroscopy techniques. Current and future course modules include ICP-MS and AA spectroscopy.

Connecting Performance Improvement to Increased Production in GC/MS Analytical Workflows

On-demand

Angie Smith-Henry & Gustavo Serrano (Agilent)

This webinar goes over some of the Ultra Inert GC columns, liners and supplies, including gold-seals and novel gold-coated ferrules that are critical to achieve optimal performance even for low-trace level analysis and deliver consistent reliable results.

Passive Sampling and Its Pivotal Role in ʹGreenerʹ Sampling of VOCs

On-demand

Nicola Watson (Markes International)

This webinar introduces TD and discusses how the options available for passive sampling can be best applied to a variety of VOCs in a range of situations. The webinar also discusses the advantages and disadvantages of each option, with tips and tricks for successful measurement.

Advancements and Key Parameters for EPA 8260 and EPA 524.2 using GC/MS with Purge and Trap

On-demand

Joel Kelly (Pace Analytical) and Bruce Quimby, Ph.D. (Senior Applications Scientist, Agilent)

In the first part of this presentation, Joel Kelly from Pace Analytical discusses the evolution of EPA method 8260. Bruce Quimby, from Agilent Technologies, spends the latter part of the presentation discussing data achieved using a 8860/5977B GC/MS instrument coupled with a Teledyne Tekmar Lumin purge and trap concentrator and an AQUATek liquid vial autosampler for the analysis of VOCs to the requirements of US EPA method 524.2.

Super Charge your Method Development with a Quick, Easy Universally Compatible LC and LC/MS Method

On-demand

Anne Mack (Application Scientist, Agilent)

This webinar demonstrates how you can achieve enhanced performance for basic analytes under weak ionic strength mobile phase conditions, such as formic acid. A new method development tool is featured: a unique C18 bonded phase chemistry with a charged surface on 2.7 μm superficially porous particles.

Overview of Air Sampling Techniques for Environmental Contaminants

On-demand

Kristen Schultz (MilliporeSigma, Bellefonte, PA, USA)

By viewing this presentation you will gain knowledge of air sampling devices commonly used for analytical air sampling both active and passive techniques, discover features and benefits of radial passive sampling devices compared to badge type air samplers, and learn an easier way to reliably sample isocyanates – monomers and oligomers. A practical application is discussed.

After the Shut Down: Back to Business as Unusual

On-demand

Diane Amato, John Murray and Melissa Zeier (Agilent)

Discover some useful strategies for returning to lab operations following shutdowns or changes to regular business. Learn how to address checklists and schedules, asset management process opportunities, and some changes that may occur.

Understanding the Benefits of Triple Quadrupole ICP-MS in Everyday Analysis

On-demand

Daniel Kutscher and Magda Mandic (Thermo Fisher Scientific)

This webinar highlights new opportunities where triple quadrupole ICP-MS will allow you to improve performance and efficiency, but also return on investment. It is demonstrated that modern TQ-ICP-MS systems are as easy to install and operate as a single quadrupole instrument.

Advances in Liquid Chromatography Separations Employing Carbon Particles

On-demand

Cory Muraco (Merck KGaA)

This webinar focuses on recent advances, in the past two years, in 'carbon-HPLC' in the analysis of compounds classically associated with being difficult to separate by conventional 'silica-HPLC.'

Extractables and Leachables in Food Contact Material

On-demand

KC Hyland (SCIEX)

This webinar covers methods for detecting and quantifying compounds that might leach into food from packaging materials.

Maintaining Sensitivity and Peak Shape on GC and GC/MS over Time

On-demand

Angie Smith-Henry and Vanessa Abercrombie (Agilent)

This webinar delves into the sensitivity of different GC detectors — mass spectrometers (single quad and triple quad) and non-MS detectors — and optimizing the GC supplies and parameters for the best separation and peak shape as the analytes head into the detector.

Improve your Karl Fischer Titration Process for Water Determination

On-demand

Bettina Straub-Jubb (Merck KGaA) and Thomas Hitz (Mettler-Toledo)

This webinar describes how to avoid errors, get tips and tricks, and discover seamless data transfer to improve your Karl Fischer titration process for water determination.

An Introduction to Solid-State NMR as An Indispensable Analytical Tool

On-demand

Koji Yazawa, PhD (JEOL RESONANCE Inc.)

In recent years, solid-state NMR has rapidly expanded its application fields due to the development of technology and its usefulness and has become an indispensable analytical tool not only in organic chemistry such as pharmaceuticals and polymers, but also in inorganic materials and battery materials. In this webinar, we briefly introduce the basic principles and techniques of solid-state NMR, and examples of applications in chemistry and material research.

Getting your LC/GC Lab Up and Running Again

On-demand

Paul Altiero and Mark Sinnott (Agilent)

Regardless of why your lab may have been shut down, you need to get your LC and GC instruments back up and running quickly and safely. This presentation covers the information you need to get back to your important research including restart procedures, helpful service, items, support topics, and discussions on improving operational efficiency and capacity.

Extraction of New and Emerging Drugs of Abuse Prior to LC-MS or GC-MS Analysis

On-demand

Jillian Neifeld (Biotage AB)

This webinar discusses how to extract various designer drugs of abuse from urine, whole blood, oral fluid, and hair prior to LC-MS or GC-MS analysis. Specifically discussed are synthetic cannabinoids, synthetic opioids, synthetic benzodiazepines, and synthetic stimulants.

Advanced Technologies Combined for Enhanced GPC/SEC Analysis of Polymers

On-demand

Subin Damodaran and Sébastien Rouzeau (Tosoh Bioscience)

This webinar describes the latest technologies in GPC/SEC to characterize the molecular weight distribution and architecture of polymers. Understand the key parameters influencing GPC/SEC results, learn about the latest technologies in GPC/SEC-dedicated instrumentation, columns and light scattering (MALS) detection and discover how to improve the characterization of polymers.

SEE What You've Been Missing with ACQUITY PREMIER Columns: Precision Chemistries for Particles and Surfaces

On-demand

Kim Haynes and Jonathan Turner (Waters Corporation)

This presentation highlights the advantages of the ACQUITY PREMIER columns, discussing various particle technologies and their benefits in chromatographic separations.

Quality Control of Hand Sanitizers: Analysis and Identification of Listed Impurities following USP <611> and ASTM D3695 Method Recommendations using Agilent GC

On-demand

Zhang-Jie and Vanessa Abercrombie (Agilent)

In this webinar you will find out how to achieve effective analysis and identification of listed impurities following USP <611> and ASTM D3695 method recommendations for alcohol determination.

Trials and Tribulations of Fat Soluble Vitamin Analysis by UHPLC-MS/MS

On-demand

Alan Edgington (Biotage, UK)

This webinar summarizes the work performed to develop a method for the analysis of fat-soluble vitamins including vitamins A (Retinol and Beta Carotene), D (25 Hydroxy D3 and 25 Hydroxy D2), E (Alpha Tocopherol) and K (Phylloquinone and Menaquinone) in human serum.

New Analytical Strategies for the Determination of Food Quality and Safety by Automated Sample Preparation Coupled with 1D and 2D GC–MS

On-demand

Chiara Cordero (University of Turin), Giorgia Purcaro (University of Liège) & Taylor Hayward (Apeel Sciences)

In this e-seminar industry experts discuss the common problems associated with sample preparation for a variety of food applications. They discuss how these have been overcome using a powerful combination of sample extraction and enrichment, with both 1D and 2D GC coupled with mass spectrometry.

The Exposome of PFAS

On-demand

Simon Roberts (SCIEX) and Christian Lindh (Lund University)

By viewing these presentations you will be provided with an overview of PFAS - what it is, its analytical characteristics and an introduction to PFAS analysis using LC-MS/MS, hidden tips and tricks to get the best from your workflow, and some practical applications of blood and urine concentrations and toxicokinetics of PFAS in various human populations.

Elemental Analysis of e-Cigarettes: Pushing the Boundaries of ICP-MS Analysis to a New Level

On-demand

David Fishwick (Broughton Nicotine Services, UK) and James Hannan (Thermo Fisher Scientific, UK)

This presentation focuses on trace elemental analysis associated with the growing industry of Electronic Nicotine Delivery Systems (ENDS), more commonly referred to as e-cigarettes, using ICP-MS. It covers the development of robust methods for this analysis using both single and triple quadrupole ICP-MS technology.

Best Practices in Ion Chromatography

On-demand

Jonas Loof (Metrohm)

Pick up some valuable troubleshooting tips and insights into ion chromatography and its many advantages. Find out what can go wrong, what you can do to improve results, and what measures you can take to reduce instrument downtime as well as extend the instrument’s service life.

Introduction to and Practical Applications of the SCIEX Triple Quad 7500 LC-MS/MS System – QTRAP Ready

On-demand

Ian Moore and Jianru Stahl-Zeng (SCIEX)

Learn how the SCIEX 7500 System enables you to attain up to 7X greater sensitivity to quantify more trace analytes at lower levels across a broad suite of sample types and workflows.

Towards AI-Powered Cost Effective Elemental ICP-OES Analysis

On-demand

Eric Vanclay and Lindsey Whitecotton (Agilent)

In this ICP-OES webinar the presenters showcase how artificial intelligence based smart tools paired with innovative sample introduction systems can reduce sample remeasurement to improve productivity and overall performance, and simplify routine maintenance.

Trace Metals Analysis in Dietary Supplements Using ICP-MS: How to Achieve Regulatory Compliance and Minimize Contamination

On-demand

Grant Fulford and Hans Krueger (Eurofins Food Integrity and Innovation)

This presentation covers ICP-MS analysis of dietary supplements for trace metals and minimizing contamination to meet regulatory compliance. Case studies and data are presented to show the challenges that regulations for trace metals can present in ICP-MS analysis of food and dietary supplements.

Perform like a PRO: Robust ICP-OES analysis with the new iCAP PRO Series ICP-OES

On-demand

Dr Sukanya Sengupta & Nora Bartsch (Thermo Fisher Scientific)

A technique of choice for elemental analysis is inductively coupled plasma-optical emission spectroscopy (ICP-OES), which is ideally suited for a range of sample types. However, some samples present analytical challenges including high matrix samples and samples which produce complex spectrum impacting accuracy. Watch this presentation to find out how the latest ICP-OES technology can address these issues and improve your elemental analysis.

Key Notes on Citing Spectral Library Searches

Letter to the Editor

O. David Sparkman

A collection of mass spectra of known compounds and the program used to search a spectrum of an unidentified compound are two different entities. The results obtained depend on both. Full and correct citations should be the norm - find out how to do this correctly.

Smarter Sample Prep: Moving your Workflow from Manual Processing to Automation

On-demand

Dr Dan Menasco (Biotage AB)

This webinar discusses the systems and software available to address various levels of sample complexity and the transitional elements one must consider to strategically move into automating sample prep.

Titration and Lab 4.0

On-demand

Eyla Reuss (Merck KGaA) and Christian Haider (Metrohm AG)

This webinar introduces you to the advantages of the unique combination of the Omnis titration platform with the jointly developed 3S titration reagents. Find out how automated transfer of relevant data ensures data integrity and traceability.

An Industry Perspective on the Prevention of Food Fraud

On-demand

Luis Hernandez & Geoffrey Cottenet (Nestlé)

Nestlé Research has collaborated with Thermo Fisher Scientific and SGS Molecular to develop an untargeted species identification workflow based on Next Generation Sequencing (NGS), which is applicable to meat, fish and plant.

The Power of GC-TOF-MS for Food and Environmental Applications eSeminar

On-demand

Multi-speaker event

Discover how GC-TOF-MS and GC×GC-TOF-MS technologies can dramatically enhance your applications for food and environmental analysis and increase data quality and sample throughput. This on-demand eSeminar comprises two sessions: one dedicated to food analysis and the other to environmental analysis.

Food Authenticity and the AOAC INTERNATIONAL Standards and Methods Development Program

On-demand

Bert Pöpping, Joe Boison, John Szpylka and Palmer Orlandi

Viewers will be introduced to the approach taken by AOAC International’s Food Authenticity Methods (FAM) Program and to the targeted and non-targeted consensus performance standards recently adopted for methods to authenticate high priority commodities such as olive oil, honey and milk.

Ionic Liquid GC Phases - Valuable Assets in the GC Toolbox: An Overview on Recent Developments

On-demand

Len Sidisky (Senior R&D Manager Gas Separations, MilliporeSigma, Bellefonte,PA USA)

This presentation provides a look back on some of the past developments and key applications with ionic liquid stationary phases while also updating on current studies.

SPME Devices and Adsorbents – A Comparison

On-demand

Bob Shirey (MilliporeSigma, USA )

This webinar will help to increase your knowledge of solid-phase microextraction (SPME) and discover its full potential as a valuable tool for many application fields. It will introduce you to a recently developed SPME configuration demonstrating its new capabilities as compared with classical SPME fibres. You will see the differences with regards to dimensions, extraction and desorption behaviour and analytical performance.

Remote Operations: This is How We GC

On-demand

Abbey Fausett (Agilent)

Sometimes, getting into the lab just isn’t possible. Workflows and productivity shouldn’t be affected by an analyst’s proximity to the systems. This webinar will show you how Agilent's lab enables remote operations. Learn more about classic and novel ways to interact with GCs.

Routine Trace Pesticide Residue Quantitation with Comprehensive Workflows: Solutions for Success in Today’s Laboratories

On-demand

Ed George (Thermo Fisher Scientific)

This webinar describes the development and implementation of two separate complete workflow solutions based on LC-MS/MS and IC-MS/MS for the routine quantitation of pesticide residues in food products. These ready-to-go solutions have been validated in a variety of matrices across multiple laboratories.

Making the Most of your LC System

On-demand

Mark Powell (Applications Engineer, Agilent)

This on-demand webinar will cover the LC system overview, from solvent bottles to detector, with a focus on preventive maintenance and what to look out for to keep your systems running at optimal performance.

One Size Does Not Fit All: Considerations for Minimizing Matrix Effect and Maximizing Recovery for Clinical Panels Large and Small

On-demand

Dr Lee Williams (Biotage GB Limited)

This webinar discusses typical clinical matrices such as whole blood, plasma, serum, urine and oral fluid with specific emphasis on a variety of endogenous components. Matrix complexity will be illustrated and related to a variety of clinical assays, demonstrating potential impact on method robustness.

GC×GC-FID/TOF MS for the Optimization of Novel Catalytic Strategies to Improve Fuel Streams with High Aromatic Content

On-demand

Miren Pena-Abaurrea (Cepsa Research Center)

Learn the value of GC×GC with parallel detection by TOF MS and FID, and see how GC×GC offers the unique possibilities for detailed petrochemical fingerprinting.

Getting Better GC/MS Results for Maximizing Productivity in High-throughput Labs

On-demand

Angie Smith-Henry and Gustavo Serrano (Agilent)

Learn about the best columns for GC-MS analysis and how to convert to a narrower bore column for faster analysis, and how to set-up your GC (MS) system for success with the optimal supplies, tools, and strategies for running the faster analysis and maintaining a clean system for as long as possible.

Application of GC×GC-TOFMS/FID to FAME Profiling of Dairy Fat and Advantages over Traditional GC Analysis

On-demand

David Mannion (Teagasc)

Learn the value of GC×GC-TOF MS for food analysis, and how it offers the unique possibility for detailed FAMEs profiling and effective fingerprinting of complex samples, In addition, learn how cutting-edge analytical techniques can reveal hidden information from complex food samples.

Intelligent GC Systems: Remote Operations and the Future of GC

On-demand

George Reiner and Jason Ashe (Agilent, USA)

This webinar discusses the progression of smart GC features and the many benefits provided from the first GC systems to those of today. It will help you to help to increase lab productivity and reduce unplanned downtime.

New Ways of QC Process with GC Innovations

On-demand

Dieter Franke (Siegwerk)

Learn how a robust analytical experimental model and innovations in gas chromatography can result in >50% faster universal methods and how direct column heating in gas chromatography reduced sample run times.

Troubleshooting & Tips for Atomic Absorption

On-demand

Eric Vanclay (Agilent, Australia)

In this series of tutorials you will learn about types and performance of AA lamps, improving performance, maintenance, consumables and resources. Increase your knowledge of and skills in atomic absorption spectroscopy by viewing these educational presentations.

GC/MS Analysis of Aromatics in Gasoline using ASTM D5769: Set-up, Optimization, and Automated Reporting

On-demand

Jim McCurry & Craig Marvin (Agilent)

This presentation offers best practices for setting up, optimizing, and running this method on a new, cost-effective GC/MS system. Data analysis approaches are also discussed with emphasis on a new system for automated reporting of results.

Advantages of TF-SPME Sample Extraction Prior to GC-MS

On-demand

Ray Marsili (Marsili Consulting Group, USA)

The advantages of TF-SPME as an extraction technique are discussed using the following examples: comparing off-flavour chemicals in beer by sequential-SBSE and TF-SPME; analysis of vegetable oils by HS-TF-SPME; chemicals in vaping products by HS-TF-SPME; and analysis of free and glycosidically bound volatile phenolics in smoke-tainted wines.

Solving the Challenges and Workflow Dilemma of High-throughput Multi-residue Pesticide Screening Program in a Quality Control Environment

On-demand

Katie Banaszewski (NOW Foods)

By viewing this presentation you will learn about optimization of LC-MS and GC-MS workflows for pesticide analysis in food, techniques for extracting difficult food matrices, and the use of Chromeleon software to streamline sample reporting.

Determination of Paralytic Shellfish Toxins and Tetrodotoxin in Shellfish using HILIC/MS/MS

On-demand

Andrew D. Turner (Cefas Weymouth Laboratory, UK)

This webinar describes the development of a combined method to ensure the high quality of shellfish, intended for human consumption, using HILIC/MS/MS and MassHunter software.

Simplifying the Analysis of VOCs and SVOCs from Solids, Liquids and Gases: The Insider’s Guide to Thermal Desorption

On-demand

Dr Diane Turner (Anthias Consulting Limited) & Dr Helen Martin (Markes International)

This webinar walks through the stages involved in analysing samples by thermal desorption, including best practices, tips and tricks and the latest TD innovations to streamline processes and generate the highest quality data.

Ion Chromatography Solutions in the Petrochemical Industry

On-demand

Iris Reber (Metrohm, Switzerland) and Ricardo Sales Tena (BP, Spain)

Learn how ion chromatography can be used as a versatile analysis technique and discover solutions to some of the challenges faced by petrochemical labs. In addition, get to know various inline sample preparation techniques that will allow you to save valuable time and resources.

The Importance of Ultra Fast Mass Spectrometry for the Analysis of Chemical Hazards in Food & Beverages

On-demand

Peter Varelis (Shimadzu Scientific Instruments, Oceania)

This webinar highlights the importance of ultra fast mass spectrometry for the analysis of chemical hazards in food and beverages. This is discussed in the context of the regulatory requirements for the analysis of contaminants in foods and a general overview of chemical hazards in foods.

Latest Mass Spectrometry-based Trends for Identifying and Quantifying Unknown PFAS Compounds

On-demand

Lee Ferguson and Abigail Joyce (Duke University, North Carolina, USA)

In this webinar, leaders of the Ferguson Laboratory discuss a Thermo Scientific™ Orbitrap™ Mass Spectrometer-based method, which captures more meaningful data to demystify unknown PFAS compounds. Additionally, a triple-quadrupole MS method will be discussed, which achieves desired limits of detection for identified PFAS compounds.

Comprehensive Two-Dimensional Liquid Chromatography (LC×LC) for the Analysis of Bioactive Compounds in Foodstuffs

On-demand

Luigi Mondello (University of Messina, Italy)

Learn about the benefits provided by comprehensive two-dimensional LC techniques, for the separation/identification of complex food matrices, as well as how to implement LC×LC using different column combinations (e.g. NP×RP, RP×RP and HILIC×RP) and instrumental set-ups.

How to Easily Analyse Petrochemical Samples by ICP-OES

On-demand

Matthew Cassap (Thermo Fisher Scientific)

Petrochemical samples present a number of different challenges when analyzing for trace elements by ICP-OES, these include the stable introduction of the sample in to the plasma, the complex matrix and potential interferences. This webinar describes these challenges and how to easily overcome them, by the development of robust methods that produce excellent results.

Turning up the Heat on Gas Chromatography: How to Successfully Perform High Temperature GC Applications without Breaking a Sweat

On-demand

Vanessa Abercrombie (Gas Chromatography Applications Chemist, Agilent, USA)

This webinar discusses the effect temperatures above 360 °C have on the integrity of the column phase and outlines strategies for more efficient and successful high temperature applications.

Automated Solutions for Determining 3-MCPD and Glycidyl Fatty Acid Esters in Edible Oils and Fats

On-demand

Eva Walter (Walter Rau Neusser Öl und Fett AG ( A Bunge Company), Germany)

The webinar is interesting for all those who analyse, or are planning to analyse, for 3-MCPD and glycidyl fatty acid esters, who enjoy the optimization and automation of sample preparation processes or simply want to keep up with the latest developments in the field of food analysis.

Intelligent GC Systems: Remote Operations and the Future of GC

On-demand

George Reiner and Jason Ashe (Agilent, USA)

This webinar discusses the progression of smart GC features and the many benefits provided from the first GC systems to those of today. It will help you to help to increase lab productivity and reduce unplanned downtime.

A Guide to Updating HPLC Compendial Methods in Pharmaceutical Analysis

On-demand

William J. Long (Agilent, USA)

This webinar discusses how changes to compendial method, known as adjustments, are made for HPLC separations and how these adjustments can be made with or without validation. Basic (ICH) validation guidelines are also covered.

HPLC Back to Basics - A Laboratory Companion for Liquid Chromatographers

Fundamentals

Learn all about retention factor, column dead-time, retention time diagnostics, selectivity, efficiency, tailing, resolution and the fundamental resolution equation.

Better Thermal Extraction: Tips and Tricks for VDA-278 and Other Thermal Desorption – GC/MS Methods Used for Material Emissions Testing

On-demand

Kurt Thaxton (GERSTEL International Product Manager, Pyrolysis and Thermal Desorption)

You'll learn about the history and analytical basis of analytical thermal extraction for interior air quality, the current state of the art, including tips and advice for scientists and engineers that perform VDA-278 and related methods for material emissions analysis, and where these methods fit in the overall strategy for automotive air quality and where these methods are headed in the future.

LC-MS Calibration vs Tuning

Fundamentals

There are two procedures that are used to make sure that an HPLC equipped with a mass spectral detector (MS) is reporting proper mass information and that the system is properly set to detect the analyte(s) of interest.

Get more information in less time: a routine and sensitive workflow for peptide mapping and PTM analysis

On-demand

Linfeng Wu and Ning Tang (Agilent Technologies)

Learn how an integrated peptide mapping workflow solution automates and streamlines from sample preparation to data analysis.

HPLC Injection Problems

Troubleshooting Advice

I am running an isocratic method with a 250 x 4.6 mm, 10 µm particle column at 1 mL/min with a 20% acetonitrile (ACN)/buffer mobile phase. I dissolve my sample in ACN and inject. Normally my compound of interest comes out at 7.7 min. I switched to a 250 x 4.0 mm column, keeping everything else the same, but now I see a distinct hump on the front of the peak. Is this another compound or am I doing something wrong?

Buffer Preparation

Troubleshooting Advice

I use trifluoroacetic acid (TFA) to adjust the aqueous portion of my HPLC mobile phase to pH 2.5. Even with careful pH adjustment, I see changes in retention when I prepare each new batch of mobile phase. Retention seems to be consistent within a batch, but batch-to-batch variability concerns me. Can you shed any light on this problem?

Does a Guard Column Make Sense?

Troubleshooting Advice

A guard column is one of those HPLC accessories that is a bit of a mixed grill – it can be a good thing or a not-so-good thing. Let’s look at some of the different aspects of guard column use to see if they make sense for you.

A New Integrated, Sample-to-Result, Analytical Workflow for the Sensitive and Reliable Analysis of Polar Anionic Pesticides and Metabolites

On-demand

Richard Fussell and Fausto Pigozzo (Thermo Fisher Scientific)

This webinar introduces a new validated ion-chromatography triple quadrupole mass spectrometry based workflow for the robust, sensitive and reliable determination of a group of polar anionic pesticides and metabolites at low µg/kg levels, without the need for derivatization, and all in a single analysis.

Intelligent GC Systems: 10 Ways to Easy GC

On-demand

Angela Smith-Henry and Ian Eisele (Agilent, USA)

This webinar introduces a host of useful tips and tricks to streamline your daily workload leading to increased productivity with improved throughput with sample overlap, enabling you to perform easier GC. You will discover steps for high quality, accurate data – first time, every time.

What’s in The Air We Breathe? A Walk Through Canister Sampling and Analysis for Measuring Air Toxics

On-demand

Helen Martin (Thermal Desorption Product Marketing Manager, Markes International)

Listen to this series of talks addressing 'What are VOCs and Why Measure Them?', 'Choosing the Best Air Sampling Technique for Your Application', and 'A Guide to Canister Sampling'. You will learn how to choose the best sampling technique for your application, what you will need for each stage of a canister sampling cycle, and how to get the most out of your air analysis instruments.

Applications using Thin Film Solid-Phase Microextraction (TF-SPME) with Analysis by Thermal Desorption GC/MS

On-demand

Jack Stuff, Ph.D. (Manager of the Analytical Services Group - GERSTEL, Inc.)

This webinar focuses on the use of Thin Film Solid-Phase Microextraction (TF-SPME) for the analysis of a variety of sample types. TF-SPME is an extension of regular SPME, is simple to use and requires no solvent, yet is more sensitive than regular SPME due to the increased surface area and phase volume.

Intelligent GC Systems: Work Smarter not Harder

On-demand

Eric Phillips and Angela Smith-Henry (Agilent, USA)

This webinar introduces intelligent Agilent GC systems, along with consumables, demonstrating how productivity can be increased and downtime decreased for any GC operator at any experience level.

Opioids: Choosing the Best Solution for your Laboratory

On-demand

Jillian Neifeld (Applications Chemist, Biotage)

This webinar provides sample preparation solutions for synthetic opioids analysis in forensic laboratories. We discuss the opioid epidemic, extraction techniques to include supported liquid extraction and solid phase extraction, matrices that can be analysed with these techniques, as well as results obtained from the various extraction types.

New Perspectives and Technology in Pyrolysis GC-MS for Forensic and Polymer Analysis: How Smart-Ramped Pyrolysis Leads to Improved Data

On-demand

Kurt Thaxton (GERSTEL International Product Manager, Pyrolysis and Thermal Desorption)

This introductory webinar describes the hardware advances in pyrolysis-GC-MS in more detail and provides examples of improvement in data quality, using samples drawn from forensic and polymer application areas.

Not the AA Lamp Again! Troubleshooting HC Lamp Issues and Other Tips for Atomic Absorption

On-demand

Eric Vanclay (Agilent Technologies, Melbourne, Australia)

Learn how to prevent, identify and troubleshoot common Hollow Cathode (HC) lamp issues and learn valuable troubleshooting tips for atomic absorption that take the pain out of everyday operation.

How to Keep your GC/GC-MS System Performing like New

On-demand

Vanessa Abercrombie and Angela Smith-Henry (Agilent Technologies, USA)

Discover some simple strategies to help maintain a clean and healthy GC(MS) system longer, such as how utilizing guard columns can protect your analytical column and back flushing can stop heavier compounds from reaching your mass spec and keep it cleaner.

High Resolution Orbitrap MS for Detecting New Psychoactive Drugs, A User’s Perspective

On-demand

Marta Concheiro (Assistant Professor of Forensic Toxicology, John Jay College of Criminal Justice, City University of New York)

In this webinar you will learn about two analytical methods for the determination of new psychoactive stimulants in urine by liquid chromatography–high resolution mass spectrometry with Orbitrap technology.

Detección de las Nuevas Sustancias Psicoactivas mediante el espectrómetro de masas de alta resolución Orbitrap MS, perspectiva del usuario

A pedido

Marta Concheiro (Profesora Asistente de Toxicología Forense, John Jay College of Criminal Justice, City University de Nueva York)

En este seminario web aprenderá en el español sobre dos métodos analíticos para la determinación de nuevos estimulantes psicoactivos utilizando cromatografía liquida acoplada a espectrometría de masas de alta resolución con tecnología de Orbitrap™ MS.

Advances in Forensics & Toxicology eSeminar

On-demand

Tania A. Sasaki, Alex J. Krotulski, Rafael Venson, Fred Foster, Alberto Salomone & Timothy Fassette

This on-demand eSeminar sponsored by GERSTEL, SCIEX and UCT, covers topics such as drug testing of urine, pharmaceutical and drugs of abuse monitoring, designer drug detection, sample preparation techniques for opioids, and QuEChERS in DUI testing.

Overcoming the Challenges of Monitoring PAMS Hydrocarbons and Polar VOCs at Low Ambient Levels

On-demand

Peter Furdyna (New York State Department of Environmental Conservation, USA) and Rui Li (Markes International)

The presentation includes operating conditions for the Markes–Agilent PAMS autosampler/GC installed at the New York State Department of Environmental Conservation (NYSDEC) PAMS monitoring site at New York Botanical Gardens, Bronx, NY, and the rationale for these conditions. You will learn how to address the challenges in on-line monitoring of ozone precursors and discover a PAMS success story.

Analytical Approaches to Trace Elements in Water

On-demand

Michelle Gaskell (South West Water), Matthew Cassap (Thermo Fisher Scientific)

Talks include 'Validation of Metals in Clean and Waste Water by ICP-MS in Accordance to ISO:17025' and 'Elemental Analysis of Water – Which Elemental Analysis Technique is Right for My Requirements'.

Analytical Testing Strategies for Medical Use Cannabis

On-demand

Julie Kowalski (Trace Analytics), Michael Groessl (University Hospital Bern, Switzerland), Justin Steimling (Restek), Brett Taubman (Appalachian State University), Allegra Leghissa (University of Texas - Arlington), Colton Myers (Restek)

Presentations covering cannabinoid profiling and potency testing, pesticide testing, sample preparation strategies, terpene analysis and residual solvent analysis will be covered.

High-Purity Carbon Adsorbents for Sample Preparation and Chromatographic Applications

On-demand

Leidy Peña Duque (Senior Scientist, Particle Design Group) and William Betz (Research Fellow, Particle Design Group Leader)

In this webinar, we will talk about high-purity carbon adsorbents used for sample preparation applications such as gas chromatography, air sampling, SPE, and SPME. We will also explain the properties of different types of carbons and how we tailor these adsorbents for separation applications.

Metabolomic Profiling of Superfood Seeds in Bakery Products using a Benchtop GC Time-of-Flight Mass Spectrometer

On-demand

Dr Jürgen Wendt (LECO European Application and Technology Center, Berlin, Germany)

In this webinar a benchtop GC TOF-MS is used to evaluate the metabolomic profile of chia, flax and sesame seeds, looking for chemical markers to confirm the presence of such seeds in food products.

Elevate the Performance of your GC (and MS): Strategies to Improve Sensitivity and Reliability with Complex Matrix Samples

On-demand

Vanessa Abercrombie and Limian Zhao (Agilent Technologies)

This presentation describes useful strategies such as choosing the right GC column and supplies, as well as what level of sample preparation, and maintenance is required for method reliability and analytical data quality, using challenging representative applications.

Tracing the Origin of Food: Establish Food Authenticity using Elemental Profiling

On-demand

Susan Ebeler (UC Davis), Courtney Tanabe (UC Davis) and Jenny Nelson (Agilent Technologies)

Learn how elemental profiling using ICP-MS, ICP-OES, and MP-AES can be used as an approach for geographic authentication of various foods and beverages.

This is How you ICP-MS: Mastering the Art of Cone Performance

On-demand

Gareth Pearson (Agilent Technologies, Melbourne, Australia)

Learn how to select the right cones for your Agilent ICP-MS and for your laboratory’s applications, understand what impact the cone has on the analysis results and why you should choose genuine supplies for your ICP-MS. Finally, learn about best practice for cone maintenance.