To develop a more in-depth understanding of gas chromatography-mass spectrometry. Deconvolution, use of H2 as a carrier gas, and tandem mass spectrometers are covered as special topics. Learn more about the mechanisms and benefits of deconvolution for isolation of individual component responses, with examples using AMDIS from NIST.
You should take this course if you are a user of gas chromatographs who is looking to further develop their method development and troubleshooting skills in GC-MS. A key demographic are companies that provide their employees with the yearly skill set development objectives. Even though supported by management, fulfilment of these objectives is difficult to accomplish through traditional training due to scheduling issues and frequent work-related interruptions. The online tutorial approach provides a unique solution by being accessible from anywhere with internet access, and at any time.
This course covers:
Deconvolution, use of H2 as a carrier gas, and tandem mass spectrometers are covered as special topics. Learn more about the mechanisms and benefits of deconvolution for isolation of individual component responses, with examples using AMDIS from NIST. Find out the benefits and pitfalls of switching to H2 carrier gas. See how the use of two mass filters instead of one can add an extra level of confidence and improve the rejection of background interferences.
- H2 Carrier Gas
- Tandem MS
The relevant aspects of tuning a quadrupole MS for GC data acquisition are covered. An explanation of different types of tunes is provided. Example parameters and setpoints are explained as well as their effects on results. Development and use of custom tunes to meet method-specific requirements are presented as are concepts of dynamic ramping of source parameters. How to use historical tune results to track system performance changes is also explained.
This module has a complementary quiz. By correctly answering the quiz questions for all of the modules as part of the course you will be able to download your certificate of completion. Types of questions to expect are:
- In general, when does GC-MS maintenance best to be performed?
- What is not a common maintenance item related to the GC?
- What is not a common maintenance item related to the MS?
- How does one check for leakage on the high-pressure side?
- Which is not related to peak tailing?
- What items are recommended to keep a record of?
- What does system suitability mean?
- What can measure the peak shape?
- What does the best system suitability tests include?
- What does tracking system suitability results over time do?
Analytical Training Solutions, brought to you by Separation Science, is the leading global portal for fundamentals, best practice, troubleshooting and method development training for chromatographic and mass spectrometric techniques. Comprehensive, self-paced online courses and validated learning provides a unique education resource for analytical chemists. Currently, we offer HPLC training, LC-MS training, GC training and GC-MS training.