A comprehensive course in the systematic development of liquid chromatography separations using QbD principles. This section examines several quality-related issues. We give a brief overview of the validation process and consider when a method change will require re-validation.
This course is designed for practical workers in the laboratory who have the responsibility for designing new HPLC or UHPLC methods or transferring methods between laboratories. Experienced workers will get the most out of this class, but because it builds from the fundamentals, anyone with experience in HPLC or UHPLC will gain valuable knowledge.
This course covers:
This section examines several quality-related issues. We give a brief overview of the validation process and consider when a method change will require re-validation. Next, the discussion centres on method precision – how much is needed and how to improve it if precision is poor.
- Validation Highlights
- The Importance of Precision
By attending this online training course you get full access to the 38 video modules and approximately 12.5 hours of instruction. You also get handouts containing copies of all of the approximately 520 PowerPoint slides used in the class. These are arranged for easy note-taking while you view each module and give you a valuable resource for future reference.
This module has a complementary quiz. By correctly answering the quiz questions for all of the modules as part of the course you will be able to download your certificate of completion. Types of questions to expect are:
- How do we describe a validation?
- What are the ways to describe the limit of detection (LOD)?
- How do we determine the robustness of a method?
- What would be the good characteristics of a system suitability test?
- What is method precision?
- What is expected to influence method precision?
- What is the best technique for calibration?
- What is a good strategy for improving the signal-to-noise ratio (S/N)?
Analytical Training Solutions, brought to you by Separation Science, is the leading global portal for fundamentals, best practice, troubleshooting and method development training for chromatographic and mass spectrometric techniques. Comprehensive, self-paced online courses and validated learning provides a unique education resource for analytical chemists. Currently, we offer HPLC training, LC-MS training, GC training and GC-MS training.