Back-to-Basics: Selectivity

by | Liquid Chromatography

This technical article considers the factors affecting chromatographic selectivity.

In this article the topic is chromatographic selectivity. Selectivity is the ability of an HPLC method to separate two analytes from each other. Selectivity usually is abbreviated with the Greek letter α, and is calculated as: α = k2 / k1  where k1 and k2 are the retention factors, k, of the first and second peaks of a peak pair.    

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Published  May 8, 2019

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