This technical article discusses general approaches to GC response calibration and focuses on the simplest; external calibration.
The heart of quantitative analysis is proper calibration. By determining the relationship between the magnitude of a peak for a known amount of analyte in a standard, one can then use that relationship (the calibration curve) to estimate the amount of that analyte in a sample of unknown concentration. First, there are a few important points to consider. The GC system performance (behaviour) must be stable and consistent.
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