Presentation Overview
Biotherapeutic drug discovery and development is a long and expensive process that requires a wide variety of assays at high and low throughput, and in both regulated and non-regulated environments. The time and expense required to develop new biotherapeutics is highly dependent on choosing the best drug candidates to move forward through this complex process. The ability to identify the best candidates is, in turn, highly dependent on the quality of the data generated from the assays that monitor the drug candidates' Critical Quality Attributes.
This presentation focuses on how automation can improve the probability of successfully and efficiently moving the best candidates forward by improving data quality, minimizing errors, reducing labor costs, and ensuring seamless transfer of assays between labs, even when these labs have different regulatory requirements. The AssayMAP Bravo is an automated microchromatography-based protein sample preparation platform that can be used to perform the assays required for drug development from target identification to manufacturing QC. This automation platform is designed to be easy to use, enable walk-up operation, come with pre-optimized applications for a wide variety of workflows, simplify documentation, and be used in both non-regulated and regulated (optional 21CFR part 11 enabling features) labs so it can be used across the entire drug development process.
From this presentation and associated resources, you will learn how:
- The power of automated protein sample prep can be leveraged by non-automation experts
- A wide variety of sample prep workflows can be addressed with a small footprint automation platform
- A single automation platform can be used across the entire drug discovery/development process in regulated and non-regulated labs
In addition to the webinar, you will also be able to download a several useful resources related to the AssayMAP Bravo.
Citation Index
This citation index provides access to the bibliographic information for all the peer-reviewed publications and Agilent application notes, as of December 2023, that use the AssayMAP Bravo for protein sample preparation.
Brochure
Agilent AssayMAP Bravo Platform
Automated protein and peptide sample preparation for mass spec analysis
Selection Guide
Agilent AssayMAP Bravo Cartridges for Automated Protein Sample Preparation Workflows
Product Information
Automated sample preparation for LC/MS analyses in biopharmaceutical workflows
Presenter:
Kenda LJ Evans, Ph.D.
Automation Workflow Specialist, Agilent
Kenda received her Ph.D. from The University of Texas Health Science Center in San Antonio in the field of pharmacology with a focus on the signal transduction pathway for the Serotonin 1A (5-HT1A) receptor. Kenda’s post-doctoral work occurred at the University of Houston School of Pharmacy where she studied the effects of inverse agonists and antagonists on Beta receptors in both respiratory and cardiovascular models. Kenda then joined Encysive Pharmaceuticals where she was the lead for the high-throughput screening team as well as project manager for target drugs. Following this, Kenda joined PerkinElmer as a high throughput screening field application scientist. For more than thirteen years now, Kenda has been a part of the Automation Team at Agilent and is currently in the role of Automation Workflow Specialist where she is helping researchers find the right solution for their automation needs and working to enable more fully applicated workflows.
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