Applications Guides

Thermal Desorption Applications Guides

Learn how thermal desorption can be used for key applications across a multitude of industries

Thermal desorption (TD) overcomes the drawbacks of conventional sample preparation techniques such as solvent extraction. Specifically, it:

  • gives greater sensitivity than these techniques
  • can be used for a wider range of compound classes
  • is applicable to a wide range of sample types
  • is safer and more environmentally friendly than solvent extraction
  • is easily automated
  • is easy to validate
  • complies with key standard methods

Developed for GC-MS scientists analyzing volatile and semi volatile organic compounds (VOCs and SVOCs) in air and materials, who need method-compliance and increased throughput, the versatile Markes Thermal Desorption portfolio is designed for targeted and untargeted analysis and is compatible with the widest range of sample types and analytes (C2 and C44) on a single platform. Unlike other TD technologies, Markes' sustainable instruments reduce costs by at least 50% per sample by enabling cryogen-free, solvent-free, and cylinder-free operations.

These applications guides provide an overview of the versatility of thermal desorption for gas chromatography and include:

Environmental Monitoring
Monitoring organic chemicals in the air, whether they arise from anthropogenic or natural sources, is vital for assessing everything from their impact on human health to their role in global climate. This comprehensive applications guide describes how TD can be used to monitor compounds in a wide range of scenarios across the field of environmental monitoring.

Food and Drink
This applications guide describes how TD can be used for key applications in the field of food and drink VOC profiling, covering everything from comparing brands of cheese to improving the shelf-life of ready‑to‑eat fresh-cut fruit.

Fragrance and Odor Profiling
This applications guide describes how TD can be used for key applications in the field of fragrance and odor profiling, covering everything from its use for rapid quality control in the tobacco industry to monitoring how the chemicals released from air fresheners change over time.

Consumer Environmental Health
This applications guide describes how TD and related sampling techniques can be used to rapidly produce meaningful information on chemical emissions from a variety of materials. In many scenarios, such analyses are carried out in accordance with national and international standard methods.

Automotive Studies
Concern over passenger health and safety because of poor vehicle interior air quality (VIAQ) has led to regulations on the materials used in vehicles and the development of associated sampling and analytical methods. This applications guide shows how TD can be applied to a range of applications in the automotive industry. Examples covered include whole air testing of car cabins, direct desorption of small samples, and chamber/bag methods for certification and screening.

Defense and Forensic
The first section of this applications guide describes how TD can be applied to the detection of chemical agents. The second section describes how TD can be applied to forensic studies from the analysis of shotgun propellant to the analysis of fire debris for accelerants.

Biological Profiling
This applications guide describes how TD is being applied to advanced research into human health, atmospheric chemistry, and chemical ecology, covering everything from the effect of stress on breath VOC profiles to the ecological role of herbivore-induced plant volatiles.


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