Effective API analysis using UHPLC-UV and a single quadrupole mass detector
Learn how to confirm the identity of related impurities and a genotoxic impurity in a drug substance using a single quadrupole mass detector.
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Learn how to confirm the identity of related impurities and a genotoxic impurity in a drug substance using a single quadrupole mass detector.
Analytical method for clinical research for the quantification of four immunosuppressants in human blood by liquid chromatography-tandem mass spectrometry
This application describes an easy, fast, and effective method using QuEChERS for the quantitative analysis of benzodiazepines in whole blood.
Discover a method for the determination of genotoxic nitrosamines in Valsartan according to Chinese Pharmacopoeia and US FDA recommended methodology.
Shimadzu's latest issue covers selected analytical applications as well as the latest product information.
Performance evaluation of a static headspace autosampler for residual solvent content analysis in water-soluble and water-insoluble pharmaceuticals
Here the analysis of irbesartan and amlodipine besilate was performed using Nexera™-i MT with results showing the reliable transfer of the listed analytical conditions for these two...
In this study, an immunoaffinity high resolution accurate mass (HRAMS) assay is presented as a complementary analytical technique for signature peptide quantification. The assay performance is measured...
In this technical note the in-vitro metabolism of a model therapeutic peptide Bivalirudin was investigated to highlight the new peptide catabolism workflow features of MetabolitePilot 2.0 software.
In this technical note the ADC specific workflow features of the new MetabolitePilot 2.0 were used to identify payload products and metabolites from two noncleavable linker ADCs...
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