Password Reminder
 
 

Your Basket contains: No items

 
 
 

Welcome to Separation Science

 

Separation Science is the leading global portal for fundamentals, best practice and troubleshooting information for users of chromatographic and mass spectrometric techniques. Featuring articles, applications, webinars, workshops and conferences, Separation Science is the industry's 'go to' information resource.

 
 
 
 
 
 
 
 

QuEChERS: Beyond the Basics

QuEChERS is a sample preparation approach that was designed to be easy, cheap but effective and rugged at the same time. It is most often used for pesticide residue analysis but its beneficial features have assisted it in branching to other fields such as environment, bioanalytical and clinical. QuEChERS was originally designed for fruits and vegetables and proven to work especially well for high water content fruits and vegetables (>80 %) with slightly acid pH.  However, there are commodities that don’t fit into this food type. 

 

Development of A Rapid Liquid Chromatography Tandem Mass Spectrometry Method for The Determination of Triclosan in Animal Tissue Matrices

A rapid LC–MS–MS method for the quantification of triclosan in animal tissue samples has been developed. This method uses large volume injection, ESI negative mode and a Poroshell LC column to improve the method limits of detection (LOD) and quantification (LOQ). The method is robust and has no complicated sample preparation steps. 

 

 
 
 

Quantitation of Antibiotics and Insecticides in Poultry Feed using Liquid Chromatography Tandem Mass Spectrometry

For decades, antibiotics have been added to livestock feeds in low doses to serve as growth promoters. Antibiotics have recently been shown to accumulate in poultry feathers, which is significant because poultry feathers serve as a high protein ingredient in animal feed, such as poultry feed.

 

Investigating Matrix Interference in Analysis of Antiarrhythmic Cardiac Drugs in Plasma

For efficient therapeutic drug monitoring, it is important for clinicians to have access to fast and robust analytical methods for accurate assessment of drug efficacy. Industrial trends toward highly specific LC/MS applications over traditional immunoassay have resulted in the need for high-speed chromatographic assays along with simplified sample preparation methods.

 

Fully Automated Determination of The Permanganate Index in Accordance with DIN EN ISO 8467

Metrohm presents a method for completely automated determination of the permanganate index according to DIN EN ISO 8467 (DIN 38409-5). The determination of the permanganate index is a standard application performed in almost all water laboratories but keeping the quality of sample preparation consistent — including the time-critical heating of samples — is a challenge.

 

1 to 3 of 181

 
 
 

Fundamentals of HPLC (Online)

10 Jun 2013 - 14 Jun 2013 08:00 - 10:30

LIVE ON THE WEB

Price: US$597

Are you new to HPLC — or do you supervise new users of HPLC? This on-line course taught by world-class experts is an opportunity to give new users a firm grounding in the fundamentals of HPLC economically and with minimum disruption to work schedules. "Fundamentals of HPLC" is intended for beginning chromatographers. No hands-on LC experience is required, but attendees should have a solid grasp of basic chemistry.

 

Advanced HPLC Method Development (Online)

09 Sep 2013 - 25 Sep 2013 08:00 - 10:30

LIVE ON THE WEB

Price: US$997

If you've ever wished that HPLC method development were more logical and methodical, this is the course for you. Attendees should have at least one year of HPLC experience in the laboratory and at least some involvement in developing new methods or troubleshooting older ones. This course is for chromatographers who want to develop better methods faster and less expensively.

 

HPLC Basics, Equipment, and Troubleshooting (Online)

10 Sep 2013 - 26 Sep 2013 08:00 - 10:30

Venue: Live on the web
Price: US$997

If you use chromatography on the job and would like a better understanding of how it works, "HPLC Basics, Equipment, and Troubleshooting" is the course for you. It's designed for chemists and biochemists who use HPLC as a regular part of their jobs, but technicians with some HPLC experience will also find the course valuable. No previous HPLC training is assumed; however, much of the course will appeal to the experienced chemists who want a firm grounding in the basics of HPLC.

 
 
 
 

Fast GC – Reducing Your Analysis Time, Increasing Your Sample Throughput

Presenter: Ruth Jones (Thermo Fisher Scientific, UK)
In collaboration with Thermo Fisher Scientific

22 May, 2013

In this webinar, we will discuss the move from conventional to fast GC through the use of shorter, narrower columns. Consideration in system parameters that need to be made in order to maintain quality of results will be discussed, and a number of applications showing the move to fast GC presented. 

 

Screening, Identification and Quantitation of Veterinary Drugs by LC QQQ and LC QTOF

Presenter: Dr Thomas Glauner (LC/MS Food Segment Scientist, Agilent Technologies)
In collaboration with: Agilent Technologies

30 May, 2013

In this webinar we show results for the screening and verification of veterinary drugs in food of animal origin by both triple quadrupole MS/MS and QTOF MS/MS. The combination of UHPLC separation, highly efficient ionization and ion sampling using the iFunnel systems, allowed the sensitive detection of several classes of veterinary drugs in one analytical run. 

 

 
 
 

The Practical Essentials of GC: Solid Phase Micro-Extraction (SPME)

29 May 2013 15:00 - 16:00

15.00-16.00 GMT
Presenter: Diane Turner (Anthias Consulting)

LIVE ON THE WEB

This a 1 hour online learning seminar covering the practical essentials of solid phase micro-extraction (SPME) in gas chromatography. This is a genuine learning tool. This course covers in detail the use of SPME in GC and GC-MS analysis.

 

The Practical Essentials of GC: Thermal Desorption (TD)

05 Jun 2013 15:00 - 16:00

15.00-16.00 GMT
Presenter: Diane Turner (Anthias Consulting)

LIVE ON THE WEB

This is a 1 hour online learning seminar on the practical essentials of thermal desorption (TD) in gas chromatography. This is a genuine learning tool. This course covers in detail the use of TD in GC and GC-MS analysis.

 

Fundamentals of HPLC (Online)

07 Oct 2013 - 11 Oct 2013 08:00 - 10:30

LIVE ON THE WEB

Price: US$597

Are you new to HPLC — or do you supervise new users of HPLC? This on-line course taught by world-class experts is an opportunity to give new users a firm grounding in the fundamentals of HPLC economically and with minimum disruption to work schedules. "Fundamentals of HPLC" is intended for beginning chromatographers. No hands-on LC experience is required, but attendees should have a solid grasp of basic chemistry.

 

LC/MS Fundamentals and Applications (Online)

08 Oct 2013 - 14 Nov 2013 : - :

LIVE ON THE WEB

Price: US$1,600

LC/MS: Fundamentals and Applications is a comprehensive overview course that provides attendees with relevant, practical approaches that can be immediately applied in the lab. The theory of mass spectrometry and LC interfaces is presented to the extent necessary to understand operation of instruments but the real focus of this class is improving your ability to use LC/MS on a daily basis. 

 
 
 
 

GC Solutions #35: Activity and Decomposition

Although gas chromatography has many positive attributes as an analytical tool, its incompatibility with labile and active compounds is certainly one of its biggest weaknesses. This month we discuss evidence of sample decomposition and what we might do to improve the results.

 

 
 
 

HPLC #110: Isolating Detector Noise: Part 1

In HPLC Solutions #109 we discussed a technique to measure noise and drift for an HPLC detector. There are several possible sources of noise in the detector, and the approach to reducing or eliminating such noise depends on the noise source. For the next few HPLC Solutions installments, we’ll look at some different sources of noise.

 

 
 
 

MS Solutions #26: FAIMS/DMS Applications Overview

In last month’s edition of MS Solutions I described the technology behind Field Asymmetric Ion Mobility Spectrometry (FAIMS), also known as Differential Mobility Spectrometry (DMS). In that article we learned that ions of identical m/z value may be separated in a FAIMS/DMS device based on their mobility differences in a high potential electrical field. In this month’s article we are going to look at the incorporation of FAIMS/DMS into a conventional LC/MS system to provide an added dimension of ion separation which is orthogonal to both chromatographic and mass spectrometric separation mechanisms.

 

 
 
 

Presentations from Mass Spectrometry 2013 are now available online, providing analysts globally with access to talks given by many of the world's leading authorities on the use and application of MS techniques. For the one-off price of US$79 you can gain access to presentations describing the importance of the sample molecule when determining the correct method; how to successfully hyphenate chromatographic systems;  and the pros and cons of the various MS interfaces? Discover how to interpret and understand the data you generate, and understand how MS can be applied to various analytical challenges across market sectors and industries.

Access is for 6 months and each presentation can be viewed multiple times. For full details on this online resource and how to access it click the 'Read more' button below.

 
 

Screening, Identification and Quantitation of Veterinary Drugs by LC QQQ and LC QTOF

Presenter: Dr Thomas Glauner (LC/MS Food Segment Scientist, Agilent Technologies)
In collaboration with: Agilent Technologies

30 May, 2013

In this webinar we show results for the screening and verification of veterinary drugs in food of animal origin by both triple quadrupole MS/MS and QTOF MS/MS. The combination of UHPLC separation, highly efficient ionization and ion sampling using the iFunnel systems, allowed the sensitive detection of several classes of veterinary drugs in one analytical run. 

 

 
 
 

Titration Solutions #4: Pulsating Conductometric Titration for Assay of Alkalinity in Water

A high resolution pulsating sensor-based conductometric titration for the determination of alkalinity in water is presented. The titration, including an online graphic display of the titration plot and offline analysis of data to obtain information regarding the end point is completed in less than 500 s. Quantitative information of various species present in the sample is obtained from the titration plot. The results obtained from the proposed technique have been compared with those obtained from pH titration.

 

 
 
 
 
 
 

Eclipse Business Media Ltd, Regd in England, No. 06513189, Frederick House, Princes Court, Beam Heath Way, Nantwich, Cheshire CW5 6PQ, United Kingdom, T +44 1270 628551, dean.graimes@sepscience.com