Protein Characteristics and How They are Analysed

by | Articles, Bioclinical Analysis

This video tutorial forms part of the '(U)HPLC Analysis of Biopharmaceuticals' series offered by Tosoh Bioscience in collaboration with Separation Science.


In this tutorial you will learn which characteristics in protein-based biotherapeutics need to be analyzed and why. Furthermore, you will get to know the chromatographic modes that are employed to analyze these (critical) quality attributes and how they work.

These include:

  • Size-exclusion chromatography
  • Ion exchange chromatography
  • Hydrophilic interaction chromatography (HILIC)
  • Hydrophobic interaction chromatography (HIC)
  • Affinity chromatography

The Expert

AndreaKrumm_200These tutorials are brought to you in collaboration with Tosoh, and presented by Andrea Krumm. Andrea studied biotechnology before gaining a PhD in cancer biology. After four years as an applications specialist for optical analytical devices used in life science research, she joined Tosoh Bioscience GmbH in 2020 as a product manager for analytical columns. As such she is responsible for gathering customer requirements, application areas and addressing these with new and existing products of the analytical columns line.

Published  Feb 1, 2023

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