Protein Characteristics and How They are Analysed
Learn which characteristics in protein-based biotherapeutics need to be analyzed and why.
Protein Analysis
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Label-free proteomics performance with a mass spectrometer with single-cell sensitivity
Find out more about the next-generation performance for protein and peptide identifications with this technical note.
HPLC applications suitable for the different aspects of CQA monitoring
HPLC applications suitable for CQA monitoring, and guidance for the appropriate LC column for the different types of detection that may be required.
Methods for mAb and ADC analysis
Application notes outlining methods for monoclonal antibody and antibody-drug conjugate analysis.
ArticlesPharmaceutical AnalysisSeparation Science in collaboration with the life science business of Merck KGaA, Darmstadt, Germany
Analysis of a bispecific monoclonal antibody with SEC-MS
Bispecific T cell Engager consisting of two single-chain variable fragments linked by a nonimmunogenic five-amino-acid chain was analysed by SEC-MS
ArticlesLiquid ChromatographyPharmaceutical AnalysisSeparation Science in collaboration with Thermo Fisher Scientific
Easy characterisation workflows in therapeutic protein analysis
Learn how new technologies overcome issues with automation of peptide mapping, including PTMs, and the benefits of automation in 96-well plate format.
Fundamentals and applications of agarose resins in SEC of proteins
Size exclusion chromatography is a powerful technique for obtaining reliable information on size of biomolecules under native conditions. A white paper presenting fundamentals about analytical SEC and...
A biopharma collaboration – NIBRT and Thermo Fisher Scientific
A collaboration between Thermo Fisher Scientific and NIBRT is focused on development of analytical solutions for biopharmaceutical characterisation
Use of Superdex™ 200 Increase size exclusion chromatography columns for screening of mAb aggregates
Screening for mAb aggregation is important in the production of mAb. When performing aggregate analysis on mAbs there is often no issue when the aggregate level is...
Comparing in-solution digestion approaches to quantify therapeutic mAb modifications
Compare the results achieved using the Thermo Scientific SMART Digest kit to those obtained from classic in-solution protein digestion methods, focusing on protein sequence coverage and identified...
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