Difluoroacetic Acid as an Effective Mobile Phase Modifier for the LC-UV/MS Analysis of Proteins
Difluoroacetic acid (DFA) is discussed as a suitable alternative to TFA and FA in the LC-UV/MS analysis of proteins.
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Difluoroacetic acid (DFA) is discussed as a suitable alternative to TFA and FA in the LC-UV/MS analysis of proteins.
Three step-by-step protocols to monitor critical quality attributes (CQAs) of monoclonal antibodies were developed using adalimumab as an example.
The optimized protocol introduced in this article shows a shorter incubation time, less artifact formation, and an efficient separation of tryptic digests
Glycan and glycosylation analysis, charge variant analysis and monitoring product quality attributes are all covered in the applications.
Application notes outlining methods for monoclonal antibody and antibody-drug conjugate analysis.
Precursor ion scan (PIS) or neutral loss scan (NLS) with a triple quadrupole LC-MS was used to compare the phospholipid profiles of four mouse tissues.
Find out more about advances in online viscometry and how a new differential viscometer dramatically improves sensitivity and near immunity to pump pulses
Hydrophobic interaction chromatography (HIC) is used for the determination of drug-to-antibody ratio (DAR) of a cysteine-linked antibody drug conjugate (ADC).
Tosoh Bioscience has produced a biopharmaceutical application notebook covering applications for HPLC and UHPLC analysis of biomolecules
Tosoh Bioscience has produced a biopharmaceutical application notebook covering applications for HPLC and UHPLC analysis of biomolecules
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