Spacer Fidelity Assessments of Guide RNA by Top-Down Mass Spectrometry
A webinar on the advancement of CRISPR-based gene editing tools into biotherapeutics
Biopharma
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Understanding Metabolic Pathways Using Mass Isotopologue Analysis with HILIC Zeno MRM High-Resolution
Accurate reconstruction of metabolic pathways is an important prerequisite for interpreting metabolomics changes and understanding the diverse biological processes in disease models.
Practical strategies to decrease uncertainty in comprehensive extractables and leachables analysis by LC/MS
Learn practical strategies to decrease uncertainty in comprehensive extractables and leachables analysis by LC/MS.
Protein Characteristics and How They are Analysed
Learn which characteristics in protein-based biotherapeutics need to be analyzed and why.
Advances in Mass Spectrometry Instrument Intelligence
Learn how to develop LC/MS methods faster, ensure confidence in results and maximize uptime.
Minimization of the Required Sample Volume for Agilent RapidFire High-Throughput Mass Spectrometry System
Find out how the use of the Agilent RapidFire high-throughput MS system with tubing using a smaller id enables sample volume to be minimized.
High-Throughput Lead Discovery with Agilent RapidFire/MS Systems
In this application note a stearoyl-coenzyme A desaturase (SCD) assay is used to illustrate the power of Agilent RapidFire/MS systems for screening intractable targets.
Automated Method Development Using a High‑Throughput Mass Spectrometry System
Discover a procedure for optimizing a method for a small example molecule, cyclic AMP with the final method having a CV of <3%, greatly improved peak shape,...
Ultrafast Analysis of Levetiracetam in Serum
This application note evaluates the ability of an ultrafast SPE/MS/MS system to analyze levetiracetam in human serum.
Fragment-Based Drug Discovery: Comparing Labeled and Label-Free Screening
This application note describes screening of β-amyloid secretase (BACE-1) using fluorescence spectroscopy and ultrafast SPE/MS/MS.
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