Tips and tricks for critical quality attributes analysis of biotherapeutics by (U)HPLC - what methods are suitable for these purposes.
Stay ahead and improve your skills! Receive tailored information on new separation science methods and applications.
Register for free learning now >>
eBook highlighting a variety of applications related to the pharmaceutical and food and beverage markets, specifically highlighting the capabilities of a compact, yet powerful LC-MS system
The forum discussion will focus on impurity profiling in the development and manufacture of therapeutic proteins.
Difluoroacetic acid (DFA) is discussed as a suitable alternative to TFA and FA in the LC-UV/MS analysis of proteins.
An LC-UV/MS method is presented using a corresponding E&L certified reference material (CRM) mix for LC screening containing 21 extractables that can typically be found.
Three step-by-step protocols to monitor critical quality attributes (CQAs) of monoclonal antibodies were developed using adalimumab as an example.
The optimized protocol introduced in this article shows a shorter incubation time, less artifact formation, and an efficient separation of tryptic digests
Application notes from the routine characterization of biotherapeutics to improved targeted peptide quantification.
Glycan and glycosylation analysis, charge variant analysis and monitoring product quality attributes are all covered in the applications.
The three aspects to consider in reverse phase LC for peptide analysis: choose the right pore size, add ion-pairing agents, and perform acid wash on column
Stay ahead and improve your skills!
Be the first to know as our team will send straight to your inbox tailored information on new separation science methods and applications..